Cholesterol

27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor.

Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities. Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research.

Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing.

DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity.

Oleandrin (PBI-05204) inhibits the Na⁺, K⁺-ATPase activity with an IC₅₀ of 620 nM.

Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 (IC₅₀=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease.

Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.

Cholesterol decanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and capric acid. Cholesterol decanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.

Cholesteryl arachidonate, a lipid, is an endogenous metabolite. Cholesteryl arachidonate has antibacterial activity.

Cholesterol-PEG 600 is a synthetic cholesterol derivative and also a Aβ (1-42) binder. Cholesterol-PEG 600 promotes the fibrillogenesis of Aβ (1-42). Cholesterol-PEG 600 is applicable to the research of Alzheimer's disease.

Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester that is exported from Saccharomyces cerevisiae via a Pry1-dependent mechanism. Cholesteryl acetate binds to the CAP superfamily protein Pry1 via interactions dependent on Pry1’s caveolin-binding motif.

Cholesterylamine is a cationic lipid and cholesterol analog. Cholesterylamine mimics the membrane transport properties of cholesterol, cycles between the plasma membrane and early/recycling endosomes in mammalian cells, and serves as a platform for constructing synthetic cell surface receptors. Cholesterylamine can be used to prepare PLGA particles with surface charges for antigen binding. Cholesterylamine is applicable for drug delivery. Cholesterylamine is used in research on autoimmune diseases and allergies.

Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.

CE(16:1(9Z)) (16:1(9Z) CE) is a cholesterol ester. Plasma levels of cholesteryl palmitoleate are increased in ApoE^-/- mice exposed to cigarette smoke and in pediatric patients with biliary atresia. Cholesteryl palmitoleate has been used as a standard for the identification of cholesterol esters in human meibomian gland secretions.

Cholesterol Heptanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cholesterol Pelargonate, a Cholesterol derivative, can be used as a triggered release liposome tested.

CAP 2 (Cholesterol-amino-phosphate 2) hydrochloride is Cholesterol-amino-phosphate (CAP) lipid. CAP 2 can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads.

Cholesterol nervonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

Cholesterol-PEG2000-Folate is an excipient and can be used for the preparation of folate-conjugated PEG-liposomes.