303-43-5
Chemical Structure
Cholesteryl oleate
- CAS No.: 303-43-5
- Formula:C45H78O2
- Molecular Weight:651.10
IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl oleate
InChIKey: RJECHNNFRHZQKU-RMUVNZEASA-N
SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cholesteryl oleate | 99.0% | Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing. | ||||||||||||||||||||
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Cholesteryl oleate-d7 | 99% | Cholesteryl oleate-d7 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing. The product specifications provided below refer solely to the active content of Cholesteryl oleate-d7. |
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Cholesteryl oleate-d7-1 | Cholesteryl oleate-d7-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing. | |||||||||||||||||||||
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-
Similarity Score 1.00
HY-W127403Cholesteryl elaidate -
Similarity Score 0.99
HY-165869ACholesteryl 11(Z)-vaccenate -
Similarity Score 0.99
HY-166276Cholesteryl petroselinate -
Similarity Score 0.99
HY-166285Cholesteryl petroselaidate -
Similarity Score 0.97
HY-146779S16:1 Cholesteryl ester-d7 -
Similarity Score 0.97
HY-W127316Cholesteryl trans-9-hexadecenoate -
Similarity Score 0.95
HY-133962Cholesteryl erucate -
Similarity Score 0.95
HY-165869Cholesteryl 11(E)-vaccenate -
Similarity Score 0.95
HY-165881Cholesteryl brassidate -
Explore the MedChemAI to find more analogs
References
- [1]. Suñé-Pou M, et, al. Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy. Int J Nanomedicine. 2018 May 30;13:3223-3233. [Content Brief]
- [2]. Rudel LL, et al. Hepatic origin of cholesteryl oleate in coronary artery atherosclerosis in African green monkeys. Enrichment by dietary monounsaturated fat. J Clin Invest. 1997 Jul 1;100(1):74-83. [Content Brief]
- [3]. Souza SL, et al. Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid. Chem Phys Lipids. 2011 Oct;164(7):664-71. [Content Brief]
- [4]. Li J, et al. Integration of lipidomics and transcriptomics unravels aberrant lipid metabolism and defines cholesteryl oleate as potential biomarker of prostate cancer. Sci Rep. 2016 Feb 11;6:20984. [Content Brief]
