1631985-09-5
Chemical Structure
Alkyne Cholesterol
- CAS No.: 1631985-09-5
- Formula:C26H40O
- Molecular Weight:368.60
IUPAC Name: (2R,3S,5R)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: XKTTVPVQZLOVKH-XSLNCIIRSA-N
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC#C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
Biological Activity: Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Alkyne Cholesterol | 99.96% | Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization. | ||||||||||||||||||||
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References
- [1]. Katherine Windsor, et al. Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome. J Lipid Res. 2013 Oct;54(10):2842-50. [Content Brief]
- [2]. Katherine Windsor, et al. Assay of protein and peptide adducts of cholesterol ozonolysis products by hydrophobic and click enrichment methods. Chem Res Toxicol. 2014 Oct 20;27(10):1757-68. [Content Brief]
- [3]. Alkyne Cholesterol.
