HPA-IN-2
HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 8.2 μM and 450.7 μM against HPA and α-glucosidase, respectively.
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- CAS. Nr.: 2885971-91-3
- Formel: C33H36N4O10
- Molecular Weight:648.66
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 8.2 μM (HPA), 450.7 μM (α-glucosidase)[1]
In Vitro
HPA-IN-2 (Compound 2a-1) has four hydrogen bonds interacting with HPA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS. Nr. 2885971-91-3
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Molecular Weight 648.66
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Formel C33H36N4O10
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SMILES
O=C(NCC1=CN(N=N1)CCCCCCO[C@@H]2CC3=CC(O)=CC(O)=C3O[C@@H]2C4=CC(O)=C(C(O)=C4)O)/C=C/C5=CC=C(C(O)=C5)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)