Chinese gallotannin 

Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a K_i of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes^[1].

Ki: 0.82 μg/mL (Human Salivary α-Amylase)^[1]
IC50: 2.3 μg/mL (Porcine Pancreatic α-Amylase), 128.9 nM (Telomerase), 3.0 μM (Fatty acid synthase), 6.9 μM (α-Ketoglutarate-Dependent Dioxygenase AlkB), 7.8 μM (5α-Reductase), 24.2 μM (Poly(ADP-ribose) Glycohydrolase)^[1]

1701.20

C₇₆H₅₂O₄₆

5424-20-4

O=C(C1=CC(OC(C2=CC(O)=C(C(O)=C2)O)=O)=C(C(O)=C1)O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@H]3OC(C4=CC(OC(C5=CC(O)=C(C(O)=C5)O)=O)=C(C(O)=C4)O)=O)COC(C6=CC(OC(C7=CC(O)=C(C(O)=C7)O)=O)=C(C(O)=C6)O)=O)OC(C8=CC(OC(C9=CC(O)=C(C(O)=C9)O)=O)=C(C(O)=C8)O)=O)OC(C%10=CC(OC(C%11=CC(O)=C(C(O)=C%11)O)=O)=C(C(O)=C%10)O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Szabó K, et al. Gallotannins are non-specific inhibitors of α-amylase: Aggregates are the active species taking part in inhibition. Chem Biol Drug Des. 2021 Feb;97(2):349-357.  [Content Brief]