1. PI3K/Akt/mTOR
  2. PI4K

PI4KIIIbeta-IN-10 

Cat. No.: HY-100198 Purity: 98.21%
Data Sheet SDS Handling Instructions

PI4KIIIbeta-IN-10 is the most potent PI4KIIIβ inhibitor currently reported, with very minor off-target inhibition of PI4KIIIβ related lipid kinases (IC50 = 3.6 nM).

For research use only. We do not sell to patients.
PI4KIIIbeta-IN-10 Chemical Structure

PI4KIIIbeta-IN-10 Chemical Structure

CAS No. : 1881233-39-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO $366 In-stock
1 mg $150 In-stock
5 mg $350 In-stock
10 mg $550 In-stock
25 mg $1100 In-stock
50 mg $1700 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Description

PI4KIIIbeta-IN-10 is the most potent PI4KIIIβ inhibitor currently reported, with very minor off-target inhibition of PI4KIIIβ related lipid kinases (IC50 = 3.6 nM). IC50 value: 3.6 nM Target: PI4KIIIβ in vitro: PI4KIIIbeta-IN-10 is the most potent PI4KIIIβ inhibitor currently reported, with very minor off-target inhibition of PI4KIIIβ related lipid kinases. PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2γ (IC50 1 μM), PI3Kα (10 μM), and PI4KIIIα (3 μM), and <20% inhibition at concentrations up to 20 μM for PI4K2α, PI4K2β, and PI3Kβ. PI4KIIIbeta-IN-10 is also the most effective antiviral compound in a cellular model of hepatitis C virus replication, with the best balance of antiviral potency and low cellular toxicity[1].

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1027 mL 10.5135 mL 21.0270 mL
5 mM 0.4205 mL 2.1027 mL 4.2054 mL
10 mM 0.2103 mL 1.0513 mL 2.1027 mL
References
Molecular Weight

475.58

Formula

C₂₂H₂₅N₃O₅S₂

CAS No.

1881233-39-1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 30 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
PI4KIIIbeta-IN-10
Cat. No.:
HY-100198
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