1. PROTAC
  2. Ligand for E3 Ligase
  3. Nutlin carboxylic acid

Nutlin carboxylic acid (Synonyms: MDM2 ligand 1; E3 ligase Ligand 16)

Cat. No.: HY-128837
Handling Instructions

Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. Nutlin carboxylic acid (MDM2 ligand 1) can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

Nutlin carboxylic acid Chemical Structure

Nutlin carboxylic acid Chemical Structure

CAS No. : 2249750-27-2

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Description

Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. Nutlin carboxylic acid (MDM2 ligand 1) can be connected to the ligand for protein by a linker to form PROTACs[1].

IC50 & Target

MDM2

 

Molecular Weight

639.53

Formula

C₃₂H₃₂Cl₂N₄O₆

CAS No.

2249750-27-2

SMILES

O=C(N1C(C2=C(C=C(C=C2)OC)OC(C)C)=N[[email protected]@H](C3=CC=C(C=C3)Cl)[[email protected]]1C4=CC=C(C=C4)Cl)N5CC(N(CC(O)=O)CC5)=O.[Relative stereochemistry]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Nutlin carboxylic acid
Cat. No.:
HY-128837
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