1. PROTAC
  2. Ligand for E3 Ligase
  3. (4R,5S)-nutlin carboxylic acid

(4R,5S)-nutlin carboxylic acid (Synonyms: MDM2 ligand 2; E3 ligase Ligand 15)

Cat. No.: HY-128836
Handling Instructions

(4R,5S)-nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

(4R,5S)-nutlin carboxylic acid Chemical Structure

(4R,5S)-nutlin carboxylic acid Chemical Structure

CAS No. : 2306390-08-7

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Description

(4R,5S)-nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs[1].

IC50 & Target

MDM2

 

Molecular Weight

639.53

Formula

C₃₂H₃₂Cl₂N₄O₆

CAS No.

2306390-08-7

SMILES

O=C1N(CC(O)=O)CCN(C(N2[[email protected]@H](C3=CC=C(Cl)C=C3)[[email protected]@H](C4=CC=C(Cl)C=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
(4R,5S)-nutlin carboxylic acid
Cat. No.:
HY-128836
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