2'-Deoxy-5'-O-DMT-2'-fluorouridine
Based on 1 publication(s) in Google Scholar
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.
For research use only. We do not sell to patients.
- Purity: 98.62%
- CAS No.: 146954-74-7
- Formula: C30H29FN2O7
- Molecular Weight:548.56
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) 2'-Deoxy-5'-O-DMT-2'-fluorouridine
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Biological Activity
2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2'-Deoxy-5'-O-DMT-2'-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 146954-74-7
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Appearance Solid
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Molecular Weight 548.56
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Formula C30H29FN2O7
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Color Off-white to light yellow
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SMILES
O[C@H]1[C@@H](F)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Biogerontology
Effect of Hong Huang Tang on memory enhancement and mitigation of microgravity-induced oxidative stress in C. elegans. [Abstract]2025 Dec 16;27(1):24. PMID: 41400846
Solvent & Solubility
DMSO : 100 mg/mL (182.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8230 mL | 9.1148 mL | 18.2295 mL | 45.5739 mL |
| 5 mM | 0.3646 mL | 1.8230 mL | 3.6459 mL | 9.1148 mL | |
| 10 mM | 0.1823 mL | 0.9115 mL | 1.8230 mL | 4.5574 mL | |
| 15 mM | 0.1215 mL | 0.6077 mL | 1.2153 mL | 3.0383 mL | |
| 20 mM | 0.0911 mL | 0.4557 mL | 0.9115 mL | 2.2787 mL | |
| 25 mM | 0.0729 mL | 0.3646 mL | 0.7292 mL | 1.8230 mL | |
| 30 mM | 0.0608 mL | 0.3038 mL | 0.6077 mL | 1.5191 mL | |
| 40 mM | 0.0456 mL | 0.2279 mL | 0.4557 mL | 1.1393 mL | |
| 50 mM | 0.0365 mL | 0.1823 mL | 0.3646 mL | 0.9115 mL | |
| 60 mM | 0.0304 mL | 0.1519 mL | 0.3038 mL | 0.7596 mL | |
| 80 mM | 0.0228 mL | 0.1139 mL | 0.2279 mL | 0.5697 mL | |
| 100 mM | 0.0182 mL | 0.0911 mL | 0.1823 mL | 0.4557 mL |
2'-Deoxy-5'-O-DMT-2'-fluorouridine Related Classifications
HY-W008662 Related Classifications
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