5'-O-DMT-dT
Based on 1 Customer Validation
5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 40615-39-2
- Formula: C31H32N2O7
- Molecular Weight:544.59
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
5'-O-DMT-dT reacts with specific silane reagents to form derivatives, which are then attached to a solid support. Through multiple reaction steps, it participates in the synthesis, deprotection, and purification processes of oligonucleotides to obtain the target oligonucleotide products[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 40615-39-2
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Appearance Solid
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Molecular Weight 544.59
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Formula C31H32N2O7
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Color White to off-white
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SMILES
O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5
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Synonyms
5'-O-(4,4'-Dimethoxytrityl)thymidine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (183.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8362 mL | 9.1812 mL | 18.3624 mL | 45.9061 mL |
| 5 mM | 0.3672 mL | 1.8362 mL | 3.6725 mL | 9.1812 mL | |
| 10 mM | 0.1836 mL | 0.9181 mL | 1.8362 mL | 4.5906 mL | |
| 15 mM | 0.1224 mL | 0.6121 mL | 1.2242 mL | 3.0604 mL | |
| 20 mM | 0.0918 mL | 0.4591 mL | 0.9181 mL | 2.2953 mL | |
| 25 mM | 0.0734 mL | 0.3672 mL | 0.7345 mL | 1.8362 mL | |
| 30 mM | 0.0612 mL | 0.3060 mL | 0.6121 mL | 1.5302 mL | |
| 40 mM | 0.0459 mL | 0.2295 mL | 0.4591 mL | 1.1477 mL | |
| 50 mM | 0.0367 mL | 0.1836 mL | 0.3672 mL | 0.9181 mL | |
| 60 mM | 0.0306 mL | 0.1530 mL | 0.3060 mL | 0.7651 mL | |
| 80 mM | 0.0230 mL | 0.1148 mL | 0.2295 mL | 0.5738 mL | |
| 100 mM | 0.0184 mL | 0.0918 mL | 0.1836 mL | 0.4591 mL |
5'-O-DMT-dT Related Classifications
HY-20140 Related Classifications
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