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  2. DNA/RNA Synthesis Phosphoramidites
  3. Di-tert-butyl diisopropylphosphoramidite

Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

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Di-tert-butyl diisopropylphosphoramidite

Di-tert-butyl diisopropylphosphoramidite Chemical Structure

CAS No. : 137348-86-8

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Description

Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

Masse moléculaire

277.39

Formule

C14H32NO2P

CAS No.
Appearance

Liquid (Density: 0.879 g/cm3)

Color

Colorless to light yellow

SMILES

CC(C)N(C(C)C)P(OC(C)(C)C)OC(C)(C)C

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvant et solubilité
In Vitro: 

DMSO : ≥ 100 mg/mL (360.50 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6050 mL 18.0252 mL 36.0503 mL
5 mM 0.7210 mL 3.6050 mL 7.2101 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation

Purity: 98.82%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6050 mL 18.0252 mL 36.0503 mL 90.1258 mL
5 mM 0.7210 mL 3.6050 mL 7.2101 mL 18.0252 mL
10 mM 0.3605 mL 1.8025 mL 3.6050 mL 9.0126 mL
15 mM 0.2403 mL 1.2017 mL 2.4034 mL 6.0084 mL
20 mM 0.1803 mL 0.9013 mL 1.8025 mL 4.5063 mL
25 mM 0.1442 mL 0.7210 mL 1.4420 mL 3.6050 mL
30 mM 0.1202 mL 0.6008 mL 1.2017 mL 3.0042 mL
40 mM 0.0901 mL 0.4506 mL 0.9013 mL 2.2531 mL
50 mM 0.0721 mL 0.3605 mL 0.7210 mL 1.8025 mL
60 mM 0.0601 mL 0.3004 mL 0.6008 mL 1.5021 mL
80 mM 0.0451 mL 0.2253 mL 0.4506 mL 1.1266 mL
100 mM 0.0361 mL 0.1803 mL 0.3605 mL 0.9013 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
Di-tert-butyl diisopropylphosphoramidite
Cat. No.:
HY-W009354
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