934660-93-2
934660-93-2
Chemical Structure
Cobimetinib
Synonym(s): GDC-0973; XL518
- CAS No.: 934660-93-2
- Formula:C21H21F3IN3O2
- Molecular Weight:531.31
IUPAC Name: (S)-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone
InChIKey: BSMCAPRUBJMWDF-KRWDZBQOSA-N
SMILES: OC1([C@H]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O
Biological Activity: Cobimetinib (GDC-0973, RG7420) is a potent, selective and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cobimetinib | 99.81% | Cobimetinib (GDC-0973, RG7420) is a potent, selective and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1. | ||||||||||||||||||||
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Cobimetinib (Standard) | ≥98% | Cobimetinib (Standard) is the analytical standard of Cobimetinib. This product is intended for research and analytical applications. Cobimetinib (GDC-0973, RG7420) is a potent, selective and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1. | ||||||||||||||||||||
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Cobimetinib-d4 hydrochloride | 99.26% | Cobimetinib-d4 hydrochloride is deuterated labeled Cobimetinib (HY-13064). Cobimetinib (GDC-0973, RG7420) is a potent, selective and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1. | ||||||||||||||||||||
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