480-41-1
480-41-1
Chemical Structure
Naringenin
- CAS No.: 480-41-1
- Formula:C15H12O5
- Molecular Weight:272.25
IUPAC Name: (S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
InChIKey: FTVWIRXFELQLPI-ZDUSSCGKSA-N
SMILES: O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=CC(O)=C13
Biological Activity: Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
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Naringenin | 99.28% | Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity. | ||||||||||||||||||||
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Naringenin-d4 | 99.9% | Naringenin-d4 is the deuterated version of Naringenin (HY-N0100). Naringenin shows strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity. | ||||||||||||||||||||
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(RS)-Sakuranetin | (RS)-Sakuranetin is the racemate of Sakuranetin (HY-N3006). | |||||||||||||||||||||
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Steppogenin | 99.49% | Steppogenin is a potent inhibitor of HIF-1α and DLL4, with IC50 values of 0.56 and 8.46 μM, respectively. Steppogenin can be sued for the research of angiogenic diseases, such as those involving solid tumors. | ||||||||||||||||||||
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(-)-Pinocembrin | 99.93% | (-)-Pinocembrin exhibits anti-mycobacterium activity against mycobacteriuum tuberculosis H37Ra with an IC50 value of 1.11 mg/mL in dormant phase and 1.21 mg/mL in active phase, respectively. (-)-Pinocembrin has potent antiproliferative activity with IC50 values of 1.88-11.00 mg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines. | ||||||||||||||||||||
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Pinocembrin (Standard) | 99.72% | Pinocembrin (Standard) is the analytical standard of Pinocembrin. This product is intended for research and analytical applications. Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties. | ||||||||||||||||||||
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Eriodictyol | 99.55% | Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases. | ||||||||||||||||||||
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(±)-Eriodictyol | 99.9% | (±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases. | ||||||||||||||||||||
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5,7,2′,6′-Tetrahydroxyflavanone | 5,7,2 ',6 '-Tetrahydroxyflavanone is an extract isolated from Scutellaria baicalensis. 5,7,2 ',6 '-Tetrahydroxyflavanone has significant antibacterial activity against gram-positive bacteria. 5,7,2 ',6 '-Tetrahydroxyflavanone can be used to study the treatment of inflammatory diseases . | |||||||||||||||||||||
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(2S)-5,7,2',5'-Tetrahydroxyflavanone | (2S)-5,7,2',5'-Tetrahydroxyflavanone (Compound 6) is a flavanone that can be found in the roots of Scutellaria amabilis HARA. Flavanone possesses numerous biological activities, including antibacterial, anti-inflammatory, antitumor, and antioxidant effects. | |||||||||||||||||||||
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Isosakuranetin | 99.96% | Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker. | ||||||||||||||||||||
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(R)-Isosakuranetin | 99.56% | (R)-Isosakuranetin is an isomer of Isosakuranetin (HY-N2131). Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker. | ||||||||||||||||||||
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(±)-Pinocembrin | 99.68% | (±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line. | ||||||||||||||||||||
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5-O-Methylnaringenin | 98.0% | 5-O-Methylnaringenin is a flavonoid compound. 5-O-Methylnaringenin is isolated from chloroacetic acid . | ||||||||||||||||||||
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Sakuranetin | 99.94% | Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury. | ||||||||||||||||||||
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(2S)-5,7,3',5'-Tetrahydroxyflavanone | (2S)-5,7,3',5'-Tetrahydroxyflavanone ((2S)-3',5,5'7-Tetrahydroxyflavanone) is a porcine pancreatic lipase modulator with an IC50 of >200 μM against porcine pancreatic lipase. (2S)-5,7,3',5'-Tetrahydroxyflavanone interacts with an enzyme involved in triglyceride hydrolysis. | |||||||||||||||||||||
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Poriol | 99.12% | Poriol is a flavonoid isolated from Pseudotsuga sinensis. | ||||||||||||||||||||
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(rac)-Poriol | (rac)-Poriol (5,7,4'-Trihydroxy-6-methylflavanone) exhibits antioxidant activity, and scavenges free radical DPPH with an IC50 of 0.18 µg/mL. (rac)-Poriol inhibits the LPS (HY-D1056)-induced NO generation in RAW264.7 (98.35% inhibition rate at 10 μM), and exhibits anti-inflammatory activity. (rac)-Poriol exhibits good binding affinity with iNOS, COX-1, COX-2, TNF-α, and IL-1β. | |||||||||||||||||||||
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(±)-Naringenin (Standard) | 98.82% | (±)-Naringenin (Standard) is the analytical standard of (±)-Naringenin. This product is intended for research and analytical applications. (±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes. | ||||||||||||||||||||
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