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Cat. No.: HY-N9086A

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(rac)-Poriol

(Synonyms: 5,7,4'-Trihydroxy-6-methylflavanone)

(rac)-Poriol (5,7,4'-Trihydroxy-6-methylflavanone) exhibits antioxidant activity, and scavenges free radical DPPH with an IC₅₀ of 0.18 µg/mL. (rac)-Poriol inhibits the LPS (HY-D1056)-induced NO generation in RAW264.7 (98.35% inhibition rate at 10 μM), and exhibits anti-inflammatory activity. (rac)-Poriol exhibits good binding affinity with iNOS, COX-1, COX-2, TNF-α, and IL-1β.

For research use only. We do not sell to patients.

CAS No.: 70460-58-1
Formula: C₁₆H₁₄O₅
Molecular Weight:286.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(rac)-Poriol Chemical Structure

CAS No.: 70460-58-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All NO Synthase Isoforms :

All COX Isoforms :

All Interleukin Related Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
KB	ED₅₀	57 μg/mL Compound: NSC-180246	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 469554]

Chemical Information

CAS No. 70460-58-1
Molecular Weight 286.28
Formula C₁₆H₁₄O₅
SMILES

O=C1C2=C(C(C)=C(C=C2OC(C1)C3=CC=C(C=C3)O)O)O
Synonyms

5,7,4'-Trihydroxy-6-methylflavanone
Structure Classification
- Flavonoids
- Flavonones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sucahyo A, et al. Flavanones from ethyl acetate fraction of Caesalpinia sappan heartwood as anti-inflammatory and antioxidant: Isolation, in-vitro, and in-silico approach[C]//AIP Conference Proceedings. AIP Publishing, 2024, 3055(1).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
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(rac)-Poriol

All NO Synthase Isoforms

All COX Isoforms

All Interleukin Related Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(rac)-Poriol Related Classifications

HY-N9086A Related Classifications