70460-58-1
70460-58-1
Chemical Structure
(rac)-Poriol
Synonym(s): 5,7,4'-Trihydroxy-6-methylflavanone
- CAS No.: 70460-58-1
- Formula:C16H14O5
- Molecular Weight:286.28
InChIKey: SLFZBNOERHGNMI-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C)=C(C=C2OC(C1)C3=CC=C(C=C3)O)O)O
Biological Activity: (rac)-Poriol (5,7,4'-Trihydroxy-6-methylflavanone) exhibits antioxidant activity, and scavenges free radical DPPH with an IC50 of 0.18 µg/mL. (rac)-Poriol inhibits the LPS (HY-D1056)-induced NO generation in RAW264.7 (98.35% inhibition rate at 10 μM), and exhibits anti-inflammatory activity. (rac)-Poriol exhibits good binding affinity with iNOS, COX-1, COX-2, TNF-α, and IL-1β[1].
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(rac)-Poriol | (rac)-Poriol (5,7,4'-Trihydroxy-6-methylflavanone) exhibits antioxidant activity, and scavenges free radical DPPH with an IC50 of 0.18 µg/mL. (rac)-Poriol inhibits the LPS (HY-D1056)-induced NO generation in RAW264.7 (98.35% inhibition rate at 10 μM), and exhibits anti-inflammatory activity. (rac)-Poriol exhibits good binding affinity with iNOS, COX-1, COX-2, TNF-α, and IL-1β. | |||||||||||||||||||||
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