2756333-39-6
Chemical Structure
Palacaparib
Synonym(s): AZD-9574
- CAS No.: 2756333-39-6
- Formula:C21H22F2N6O2
- Molecular Weight:428.44
IUPAC Name: 6-fluoro-5-(4-((5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl)piperazin-1-yl)-N-methylpicolinamide
InChIKey: WXRCLFFPZXJCLS-UHFFFAOYSA-N
SMILES: O=C(C1=NC(F)=C(N2CCN(CC2)CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)C=C1)NC
Biological Activity: AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD+?breast cancer and advanced solid malignancies research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Palacaparib | 98.30% | AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD+?breast cancer and advanced solid malignancies research. | ||||||||||||||||||||
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