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Cat. No.: HY-W1060183

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trans-p-Coumaraldehyde

Name: trans-p-Coumaraldehyde
Brand: MedChemExpress
SKU: HY-W1060183
Availability: PreOrder

(Synonyms: (E)-4-Hydroxycinnamaldehyde; (E)-p-Hydroxycinnamaldehyde)

trans-p-Coumaraldehyde ((E)-4-Hydroxycinnamaldehyde) is a natural product. trans-p-Coumaraldehyde can be isolated from the seeds of Petai cina. trans-p-Coumaraldehyde exhibits potential α-glucosidase inhibitory activity. trans-p-Coumaraldehyde can be used in diabetes research.

For research use only. We do not sell to patients.

CAS No.: 20711-53-9
Formula: C₉H₈O₂
Molecular Weight:148.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

trans-p-Coumaraldehyde Chemical Structure

CAS No.: 20711-53-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

IC₅₀ & Target

^[1]

α‑glucosidase

Cellular Effect

Cell Line	Type	Value	Description	References
B16-4A5	IC₅₀	18.3 μM Compound: 11	Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control	[PMID: 27756508]
RAW264.7	IC₅₀	26.4 μM Compound: 10	Anti-inflammatory activity in murine RAW264.7 cells assessed as inhibition of LPS-induced NO production Anti-inflammatory activity in murine RAW264.7 cells assessed as inhibition of LPS-induced NO production	[PMID: 33207281]
RBL-2H3	IC₅₀	100 μM Compound: 14	Inhibitory activity against release of beta-hexosaminidase from RBL-2H3 cells Inhibitory activity against release of beta-hexosaminidase from RBL-2H3 cells	[PMID: 12951092]

In Vitro

trans-p-Coumaraldehyde exhibits moderate in silico inhibitory activity against α-glucosidase (PDB ID 3A4A), with a binding free energy of -465 kcal/mol^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 20711-53-9
Molecular Weight 148.16
Formula C₉H₈O₂
SMILES

O=C/C=C/C1=CC=C(C=C1)O
Synonyms

(E)-4-Hydroxycinnamaldehyde; (E)-p-Hydroxycinnamaldehyde
Structure Classification
- Phenols
- Monophenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Van Staden J, et al. Exocarpic acid and other compounds from tubers and inflorescences of Sarcophyte sanguinea[J]. Phytochemistry, 1992, 31(11): 3929-3931.

[2]. Maharani M, et al. Characterization of Phytocomponents of Mindi Leaf Extract and Chinese Petai Seeds by LC-HRMS and In Silico Activity Against Alpha-glucosidase[J]. Jurnal Ilmiah Kesehatan (JIKA), 2024, 6(2): 285-299.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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