1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. Cucurbitacin D

Cucurbitacin D 

Cat. No.: HY-N1986 Purity: 99.20%
Handling Instructions

Cucurbitacin D is an active component in Cucurbita texana, disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) maturation without induction of the heat shock response. Anti-cancer activity.

For research use only. We do not sell to patients.

Cucurbitacin D Chemical Structure

Cucurbitacin D Chemical Structure

CAS No. : 3877-86-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 386 In-stock
Estimated Time of Arrival: December 31
1 mg USD 85 In-stock
Estimated Time of Arrival: December 31
5 mg USD 340 In-stock
Estimated Time of Arrival: December 31
10 mg USD 580 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Description

Cucurbitacin D is an active component in Cucurbita texana, disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) maturation without induction of the heat shock response. Anti-cancer activity[1].

IC50 & Target[1]

HSP90

 

Molecular Weight

516.67

Formula

C₃₀H₄₄O₇

CAS No.

3877-86-9

SMILES

C[[email protected]@]([[email protected]@](CC=C(C(C)1C)[[email protected]@]2([H])C[[email protected]](O)C1=O)([H])[[email protected]@]2(C)C3=O)(C[[email protected]@H](O)[[email protected]]4([H])[[email protected]@](C)(O)C(/C=C/C(C)(O)C)=O)[[email protected]@]4(C3)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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Cucurbitacin D
Cat. No.:
HY-N1986
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