701225-07-2
701225-07-2
Chemical Structure
IRF1-IN-1
- CAS No.: 701225-07-2
- Formula:C22H24N4O4S
- Molecular Weight:440.52
InChIKey: YRYNHFCJTNSYHV-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=CN1CCC(NC3=CC=C(S(=O)(N4CCCCC4)=O)C=C3)=O)C=CC=C2
Biological Activity: IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IRF1-IN-1 | 99.72% | IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.58
HY-174212MXC-017 -
Similarity Score 0.57
HY-171007IRF1-IN-2 -
Similarity Score 0.53
HY-157179WAY-312491 -
Similarity Score 0.52
HY-147779VEGFR-2-IN-20 -
Similarity Score 0.52
HY-16709USP7-IN-1 -
Similarity Score 0.52
HY-157296AChE-IN-47 -
Similarity Score 0.52
HY-148135CAI/II-IN-6 -
Similarity Score 0.52
HY-147794CDK9-IN-41 -
Similarity Score 0.52
HY-160515USP7-IN-13 -
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