VEGFR-2-IN-20
VEGFR-2-IN-20 (Compound 7) is a potent inhibitor of VEGFR. VEGFR-2-IN-20 has the potential for the research of cancer diseases.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2404581-25-3
- Formel: C20H20N4O3S
- Molecular Weight:396.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
4.58 μM
Compound: 39
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 38728867] |
| HCT-116 | IC50 |
4.83 μM
Compound: 83
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37453330] |
| HepG2 | IC50 |
3.97 μM
Compound: 39
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 38728867] |
| HepG2 | IC50 |
3.97 μM
Compound: 83
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37453330] |
| MCF7 | IC50 |
4.58 μM
Compound: 83
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37453330] |
| MCF7 | IC50 |
4.83 μM
Compound: 39
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 38728867] |
Chemical Information
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CAS. Nr. 2404581-25-3
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Molecular Weight 396.46
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Formel C20H20N4O3S
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SMILES
CCN1C(C2=CC=CC=C2N=C1SCC(NC3=CC=C(C=C3)/C(C)=N/O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)