VEGFR-2-IN-20
VEGFR-2-IN-20 (Compound 7) is a potent inhibitor of VEGFR. VEGFR-2-IN-20 has the potential for the research of cancer diseases.
For research use only. We do not sell to patients.
- CAS No.: 2404581-25-3
- Formula: C20H20N4O3S
- Molecular Weight:396.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
4.58 μM
Compound: 39
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 38728867] |
| HCT-116 | IC50 |
4.83 μM
Compound: 83
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37453330] |
| HepG2 | IC50 |
3.97 μM
Compound: 39
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 38728867] |
| HepG2 | IC50 |
3.97 μM
Compound: 83
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37453330] |
| MCF7 | IC50 |
4.58 μM
Compound: 83
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37453330] |
| MCF7 | IC50 |
4.83 μM
Compound: 39
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 38728867] |
Chemical Information
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CAS No. 2404581-25-3
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Molecular Weight 396.46
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Formula C20H20N4O3S
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SMILES
CCN1C(C2=CC=CC=C2N=C1SCC(NC3=CC=C(C=C3)/C(C)=N/O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)