2523016-96-6
Chemical Structure
SK-575
- CAS No.: 2523016-96-6
- Formula:C47H53FN8O8
- Molecular Weight:876.97
IUPAC Name: N-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide
InChIKey: HPBWDZVXFSTVMR-UHFFFAOYSA-N
SMILES: O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCCCCCCCCCC(N4CCN(C(C5=CC(CC6=NNC(C7=C6C=CC=C7)=O)=CC=C5F)=O)CC4)=O
Biological Activity: SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1, with an IC50 of 2.30 nM. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SK-575 | 99.86% | SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1, with an IC50 of 2.30 nM. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations. | ||||||||||||||||||||
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Keywords
