1. Membrane Transporter/Ion Channel
    Autophagy
  2. Potassium Channel
    Autophagy
  3. Desethylamiodarone hydrochloride

Desethylamiodarone hydrochloride (Synonyms: N-desethylamiodarone hydrochloride; LB 33020 hydrochloride)

Cat. No.: HY-130353
Handling Instructions

Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM.

For research use only. We do not sell to patients.

Desethylamiodarone hydrochloride Chemical Structure

Desethylamiodarone hydrochloride Chemical Structure

CAS No. : 96027-74-6

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Description

Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM[1][2][3].

Molecular Weight

653.72

Formula

C₂₃H₂₆ClI₂NO₃

CAS No.

96027-74-6

SMILES

O=C(C1=C(CCCC)OC2=CC=CC=C12)C3=CC(I)=C(OCCNCC)C(I)=C3.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

DesethylamiodaroneN-desethylamiodaroneLB 33020LB33020LB-33020Potassium ChannelAutophagyKcsACYP3AmetaboliteantiarrhythmicInhibitorinhibitorinhibit

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Desethylamiodarone hydrochloride
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