1. Apoptosis
    Anti-infection
    Cell Cycle/DNA Damage
  2. Thymidylate Synthase
    HSV
    Nucleoside Antimetabolite/Analog
  3. Trifluridine

Trifluridine (Synonyms: Trifluorothymidine; 5-Trifluorothymidine; TFT)

Cat. No.: HY-A0061 Purity: 99.69%
Handling Instructions

Trifluridine (Trifluorothymidine; 5-Trifluorothymidine; TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral drug for herpes simplex virus (HSV) infection.

For research use only. We do not sell to patients.

Trifluridine Chemical Structure

Trifluridine Chemical Structure

CAS No. : 70-00-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 92 In-stock
Estimated Time of Arrival: December 31
50 mg USD 84 In-stock
Estimated Time of Arrival: December 31
100 mg USD 126 In-stock
Estimated Time of Arrival: December 31
200 mg USD 192 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Trifluridine:

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Trifluridine (Trifluorothymidine; 5-Trifluorothymidine; TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral drug for herpes simplex virus (HSV) infection.

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (337.61 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3761 mL 16.8805 mL 33.7610 mL
5 mM 0.6752 mL 3.3761 mL 6.7522 mL
10 mM 0.3376 mL 1.6880 mL 3.3761 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.44 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.44 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.44 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

296.20

Formula

C₁₀H₁₁F₃N₂O₅

CAS No.

70-00-8

SMILES

O=C1C(C(F)(F)F)=CN([[email protected]@H]2O[[email protected]](CO)[[email protected]@H](O)C2)C(N1)=O

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.69%

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Trifluridine
Cat. No.:
HY-A0061
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Trifluridine

Cat. No.: HY-A0061