Anti-Cancer Approved Drug Library

83 Cited Publications
Customer Review

Based on 83 publication(s) in Google Scholar

The anti-cancer drug library meticulously collects all drugs approved by FDA and other major national drug regulatory authorities for cancer treatment. These drugs cover a variety of cancer types, including but not limited to lung cancer, breast cancer, colorectal cancer, leukemia, and other common cancers. The library includes a wide range of drugs, from classic chemotherapeutic agents to cutting-edge targeted therapies and immunotherapies. It contains various types of drug compounds with different mechanisms of action. There are cytotoxic drugs that directly kill cancer cells, as well as drugs that work by modulating the tumor microenvironment, inhibiting tumor angiogenesis, and activating the immune system. This diversity provides researchers with a broad range of perspectives and options for intervention strategies.

This library can be used for basic research on cancer treatment, exploring new targets and new mechanisms of drug action; Conducting drug reuse research to look for potential therapeutic effects of existing drugs on other cancer types or diseases; Or conducting research into combination drugs to optimize cancer treatment.

MCE has collected 265 small-molecule compounds with cancer indications, which are good tools for drug repurposing.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Service

Description & Advantages

•   A unique collection of compounds with cancer-related indications for marketed drugs.

•   A useful tool for drug repurposing.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 265 FDA-approved cancer-related compounds supplied as pre-dissolved Solutions or Solid.

Solution: 253 compounds supplied in 10 mM solution, 10 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

  • PDF
  • Excel
  • SDF

Composition

Apoptosis (88)

Autophagy (71)

PDGFR (20)

Bacterial (18)

VEGFR (17)

Antibiotic (16)

c-Kit (14)

EGFR (14)

FGFR (14)

Bcr-Abl (12)

PARP (9)

HIV (6)

p38 MAPK (6)

Src (6)

Akt (5)

CDK (5)

FLT3 (5)

HDAC (5)

Mitophagy (5)

PI3K (5)

RET (5)

SARS-CoV (5)

Btk (4)

ERK (3)

Fungal (3)

HSV (3)

MEK (3)

Mitosis (3)

mTOR (3)

NF-κB (3)

Parasite (3)

PKC (3)

Raf (3)

RAR/RXR (3)

STAT (3)

Wnt (3)

c-Fms (2)

CMV (2)

CXCR (2)

Exosomes (2)

FKBP (2)

GSK-3 (2)

HSP (2)

JAK (2)

MDM-2/p53 (2)

OAT (2)

Smo (2)

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200 mg
USD 120
In-stock
Estimated to ship on August 31 More
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
Estimated to ship on August 31 More