1. Cell Cycle/DNA Damage
    Anti-infection
    Apoptosis
  2. DNA/RNA Synthesis
    HSV
    Apoptosis
  3. Aphidicolin

Aphidicolin 

Cat. No.: HY-N6733
Handling Instructions

Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA polymerase. Aphidicolin is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.

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Aphidicolin Chemical Structure

Aphidicolin Chemical Structure

CAS No. : 38966-21-1

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Description

Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA polymerase[1]. Aphidicolin is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].

Molecular Weight

338.48

Formula

C₂₀H₃₄O₄

CAS No.

38966-21-1

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Aphidicolin
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