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MRTX849 ethoxypropanoic acid

MRTX849 ethoxypropanoic acid incorporates a ligand for KRAS G12C, and a PROTAC linker. MRTX849 ethoxypropanoic acid can be used in the synthesis of PROTAC LC-2 (HY-137516). LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (IC50s between 0.25 and 0.76 μM).

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  • CAS 番号: 2561529-98-2
  • 分子式: C37H43ClFN7O5
  • 分子量:720.23
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • MRTX849 ethoxypropanoic acid Chemical Structure
    MRTX849 ethoxypropanoic acid 構造式
CAS 番号: 2561529-98-2
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    MRTX849 ethoxypropanoic acid Chemical Structure
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