BRD4 ligand-Linker Conjugate 1 TFA
Based on 1 Customer Validation
BRD4 ligand-Linker Conjugate 1 TFA (compound 106-1) is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.66%
- Formula: C30H31ClF3N7O2
- Molecular Weight:614.06
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Storage:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
Chemical Information
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Appearance Viscous Liquid
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Molecular Weight 614.06
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Formula C30H31ClF3N7O2
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Color Light yellow to brown
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SMILES
ClC1=CC=C(C2=NC3(CC3)C4=NN=C(C)N4C5=CC=C(C6=CN(CCCCCCN)N=C6)C=C25)C=C1.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (162.85 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.6285 mL | 8.1425 mL | 16.2851 mL | 40.7126 mL |
| 5 mM | 0.3257 mL | 1.6285 mL | 3.2570 mL | 8.1425 mL | |
| 10 mM | 0.1629 mL | 0.8143 mL | 1.6285 mL | 4.0713 mL | |
| 15 mM | 0.1086 mL | 0.5428 mL | 1.0857 mL | 2.7142 mL | |
| 20 mM | 0.0814 mL | 0.4071 mL | 0.8143 mL | 2.0356 mL | |
| 25 mM | 0.0651 mL | 0.3257 mL | 0.6514 mL | 1.6285 mL | |
| 30 mM | 0.0543 mL | 0.2714 mL | 0.5428 mL | 1.3571 mL | |
| 40 mM | 0.0407 mL | 0.2036 mL | 0.4071 mL | 1.0178 mL | |
| 50 mM | 0.0326 mL | 0.1629 mL | 0.3257 mL | 0.8143 mL | |
| 60 mM | 0.0271 mL | 0.1357 mL | 0.2714 mL | 0.6785 mL | |
| 80 mM | 0.0204 mL | 0.1018 mL | 0.2036 mL | 0.5089 mL | |
| 100 mM | 0.0163 mL | 0.0814 mL | 0.1629 mL | 0.4071 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.