1. PROTAC
  2. Target Protein Ligand-Linker Conjugate
  3. Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH 

Cat. No.: HY-131230 Purity: 95.09%
Handling Instructions

Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 (HY-114323). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM.

For research use only. We do not sell to patients.

Desmorpholinyl Quizartinib-PEG2-COOH Chemical Structure

Desmorpholinyl Quizartinib-PEG2-COOH Chemical Structure

CAS No. : 2292116-14-2

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50 mg USD 850 In-stock
Estimated Time of Arrival: December 31
250 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
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Description

Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 (HY-114323). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM[1].

Molecular Weight

607.68

Formula

C₃₀H₃₃N₅O₇S

CAS No.

2292116-14-2

SMILES

O=C(O)CCOCCOCCOC1=CC=C2N3C(SC2=C1)=NC(C4=CC=C(NC(NC5=NOC(C(C)(C)C)=C5)=O)C=C4)=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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Keywords:

Desmorpholinyl Quizartinib-PEG2-COOHTarget Protein Ligand-Linker ConjugateInhibitorinhibitorinhibit

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Desmorpholinyl Quizartinib-PEG2-COOH
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HY-131230
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