1. PROTAC
    Protein Tyrosine Kinase/RTK
    Apoptosis
  2. PROTAC
    FLT3
    Apoptosis
  3. PROTAC FLT-3 degrader 1

PROTAC FLT-3 degrader 1 

Cat. No.: HY-114323
Handling Instructions

PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction.

For research use only. We do not sell to patients.

PROTAC FLT-3 degrader 1 Chemical Structure

PROTAC FLT-3 degrader 1 Chemical Structure

CAS No. : 2230826-81-8

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Description

PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].

IC50 & Target

IC50: 0.6 nM (FLT-3 ITD)[1]

Molecular Weight

1020.23

Formula

C₅₂H₆₁N₉O₉S₂

CAS No.

2230826-81-8

SMILES

O=C(N[[email protected]@H](C(C)(C)C)C(N1[[email protected]](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[[email protected]@H](O)C1)=O)CCOCCOCCOC4=CC5=C(N6C(S5)=NC(C7=CC=C(NC(NC8=NOC(C(C)(C)C)=C8)=O)C=C7)=C6)C=C4

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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PROTAC FLT-3 degrader 1
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HY-114323
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