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Myriocin 

Cat. No.: HY-N6798
Handling Instructions

Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin strongly suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 µg/mL for inhibiting HCV infection.

For research use only. We do not sell to patients.

Myriocin Chemical Structure

Myriocin Chemical Structure

CAS No. : 35891-70-4

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Description

Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids[1]. Myriocin strongly suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV[2], with an IC50 of 3.5 µg/mL for inhibiting HCV infection[3].

IC50 & Target

Serine-palmitoyl-transferase (SPT)[1]

Molecular Weight

401.54

Formula

C₂₁H₃₉NO₆

CAS No.

35891-70-4

SMILES

CCCCCCC(CCCCCC/C=C/C[[email protected]@H](O)[[email protected]](O)[[email protected]](CO)(N)C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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