1190307-88-0
1190307-88-0
Chemical Structure
Sofosbuvir
Synonym(s): GS-7977; PSI-7977
- CAS No.: 1190307-88-0
- Formula:C22H29FN3O9P
- Molecular Weight:529.45
IUPAC Name: isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
InChIKey: TTZHDVOVKQGIBA-IQWMDFIBSA-N
SMILES: C[C@@]1(F)[C@H](O)[C@@H](CO[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)O[C@H]1N(C=CC(N3)=O)C3=O
Biological Activity: Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM[1].
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Sofosbuvir | 99.97% | Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM. | ||||||||||||||||||||
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Sofosbuvir (Standard) | 99.99% | Sofosbuvir (Standard) is the analytical standard of Sofosbuvir. This product is intended for research and analytical applications. Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM. | ||||||||||||||||||||
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Sofosbuvir-13C,d3 | Sofosbuvir-13C,d3 is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. | |||||||||||||||||||||
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Sofosbuvir-d6 | 98.07% | Sofosbuvir-d6 is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. | ||||||||||||||||||||
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References
