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U18666A 

Cat. No.: HY-107433 Purity: >95.0%
Handling Instructions

U18666A, a cell permeable drug, is a cholesterol synthesis and transport inhibitor.

For research use only. We do not sell to patients.

U18666A Chemical Structure

U18666A Chemical Structure

CAS No. : 3039-71-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 121 In-stock
Estimated Time of Arrival: December 31
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

U18666A, a cell permeable drug, is a cholesterol synthesis and transport inhibitor.

IC50 & Target

Cholesterol[1][2].

In Vitro

U18666A, the antiviral effect is found to result from two events: retarded viral trafficking in the cholesterol-loaded late endosomes/lysosomes and suppresse de novo sterol biosynthesis in treated infected cells. It is also observed an additive antiviral effect of U18666A with C75, a fatty acid synthase inhibitor, suggesting dengue virus relies on both the host cholesterol and fatty acid biosynthesis for successful replication[1][2].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3582 mL 11.7908 mL 23.5816 mL
5 mM 0.4716 mL 2.3582 mL 4.7163 mL
10 mM 0.2358 mL 1.1791 mL 2.3582 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

424.06

Formula

C₂₅H₄₂ClNO₂

CAS No.

3039-71-2

SMILES

C[[email protected]@]12[[email protected]]3([H])[[email protected]](CC=C1C[[email protected]@H](OCCN(CC)CC)CC2)([H])[[email protected]@]4([H])[[email protected]@](C)(C(CC4)=O)CC3.Cl

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: >95.0%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
U18666A
Cat. No.:
HY-107433
Quantity:

U18666A

Cat. No.: HY-107433