Therapeutic strategies to combat Staphylococcus aureus infections in cystic fibrosis

  • Microbes Infect. 2025 Sep-Oct;27(7):105546. doi: 10.1016/j.micinf.2025.105546.
Aygun Israyilova  1 Gabriele Trespidi  2 Viola Camilla Scoffone  2 Silvia Buroni  3
Affiliations
  • 1. Center of Excellence, Baku State University, AZ1148, Baku, Azerbaijan; Department of Biomedical Materials by ICESCO, Baku State University, AZ1148 Baku, Azerbaijan.
  • 2. Department of Biology and Biotechnology, University of Pavia, Via Ferrata, 9, 27100 Pavia, Italy.
  • 3. Department of Biology and Biotechnology, University of Pavia, Via Ferrata, 9, 27100 Pavia, Italy. Electronic address: [email protected].
Abstract

Staphylococcus aureus infections remain a great concern in people with cystic fibrosis also after the introduction of modulator therapy. Here we describe the state of the art of traditional and novel therapeutic strategies to fight both acute and chronic infections caused by sensitive and drug resistant strains.

Keywords
Cystic fibrosis; Drug resistance; New therapeutics; Staphylococcus aureus.
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