1. Apoptosis
    Immunology/Inflammation
    Autophagy
  2. FKBP
  3. Shield-1

Shield-1 

Cat. No.: HY-112210
Handling Instructions

Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein.

For research use only. We do not sell to patients.

Shield-1 Chemical Structure

Shield-1 Chemical Structure

CAS No. : 914805-33-7

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Description

Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein[1][2].

Molecular Weight

748.90

Formula

C₄₂H₅₆N₂O₁₀

CAS No.

914805-33-7

SMILES

O=C([[email protected]]1N(C([[email protected]](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[[email protected]@H](C3=CC=CC(OCCN4CCOCC4)=C3)CCC5=CC=C(OC)C(OC)=C5

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Shield-1
Cat. No.:
HY-112210
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