1. Apoptosis
    Immunology/Inflammation
    Autophagy
    PROTAC
  2. FKBP
    Ligand for Target Protein for PROTAC
  3. AP1867-2-(carboxymethoxy)

AP1867-2-(carboxymethoxy) (Synonyms: PROTAC FKBP12-binding moiety 2)

Cat. No.: HY-114420
Handling Instructions

AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules.

For research use only. We do not sell to patients.

AP1867-2-(carboxymethoxy) Chemical Structure

AP1867-2-(carboxymethoxy) Chemical Structure

CAS No. : 2230613-03-1

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules[1].

In Vitro

dTAG molecules engage FKBP12F36V and CRBN[1].

Molecular Weight

693.78

Formula

C₃₈H₄₇NO₁₁

CAS No.

2230613-03-1

SMILES

O=C([[email protected]]1N(C([[email protected]](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[[email protected]@H](C3=CC=CC=C3OCC(O)=O)CCC4=CC=C(OC)C(OC)=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
AP1867-2-(carboxymethoxy)
Cat. No.:
HY-114420
Quantity:
MCE Japan Authorized Agent: