1. PROTAC
    Autophagy
    Apoptosis
    Immunology/Inflammation
  2. Ligand for Target Protein for PROTAC
    FKBP
  3. AP1867-3-(aminoethoxy)

AP1867-3-(aminoethoxy) 

Cat. No.: HY-129363 Purity: 99.10%
Handling Instructions

AP1867-3-(aminoethoxy), the AP1867 based moiety, is a synthetic ligand for FKBP. AP1867-3-(aminoethoxy) can be used in the synthesis of PROTAC FKBP12 F36V degrader.

For research use only. We do not sell to patients.

AP1867-3-(aminoethoxy) Chemical Structure

AP1867-3-(aminoethoxy) Chemical Structure

CAS No. : 2127390-15-0

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 597 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 597 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 400 In-stock
Estimated Time of Arrival: December 31
10 mg USD 680 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2200 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3400 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

AP1867-3-(aminoethoxy), the AP1867 based moiety, is a synthetic ligand for FKBP. AP1867-3-(aminoethoxy) can be used in the synthesis of PROTAC FKBP12 F36V degrader[1].

Molecular Weight

678.81

Formula

C₃₈H₅₀N₂O₉

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 240 mg/mL (353.56 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4732 mL 7.3658 mL 14.7317 mL
5 mM 0.2946 mL 1.4732 mL 2.9463 mL
10 mM 0.1473 mL 0.7366 mL 1.4732 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6 mg/mL (8.84 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 6 mg/mL (8.84 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6 mg/mL (8.84 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
AP1867-3-(aminoethoxy)
Cat. No.:
HY-129363
Quantity:
MCE Japan Authorized Agent: