1. Anti-infection
  2. HBV

Entecavir monohydrate (Synonyms: SQ 34676; BMS 200475; SQ34676; BMS200475; SQ-34676; BMS-200475)

Cat. No.: HY-13623A Purity: 99.66%
Data Sheet SDS Handling Instructions

Entecavir monohydrate (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.

For research use only. We do not sell to patients.
Entecavir monohydrate Chemical Structure

Entecavir monohydrate Chemical Structure

CAS No. : 209216-23-9

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Description

Entecavir monohydrate (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.

IC50 & Target

EC50:3.75 nM (anti-HBV, HepG2 cell)[1]

In Vitro

BMS-200475 has a EC50 of 3.75 nM against HBV. It is incorporated into the protein primer of HBV and subsequently inhibits the priming step of the reverse transcriptase. The antiviral activity of BMS-200475 is significantly less against the other RNA and DNA viruses[1]. Entecavir is more readily phosphorylated to its active metabolites than other deoxyguanosine analogs (penciclovir, ganciclovir, lobucavir, and aciclovir) or lamivudine. The intracellular half-life of entecavir is 15 h[2].

In Vivo

Daily oral treatment with BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months effectively reduces the level of woodchuck hepatitis virus (WHV) viremia in chronically infected woodchucks[3].

Clinical Trial
NCT Number Sponsor Condition Start Date Phase
NCT01013272 The University of Hong Kong Hepatitis B, Chronic June 2007
NCT01046799 HepNet Study House, German Liverfoundation|Hannover Medical School Liver Transplantation|Hepatitis B|Liver Disease March 2008 Phase 3
NCT02777814 Sun Yat-sen University Colorectal Neoplasms May 2015 Phase 2
NCT02777801 Sun Yat-sen University Stomach Neoplasms June 2015 Phase 2
NCT01589952 Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Chronic Hepatitis B March 2012 Phase 1|Phase 2
NCT00663182 Shanghai Changzheng Hospital Hepatitis B Virus|Decompensated Cirrhosis January 2008 Phase 4
NCT01768195 Peking University Hepatitis B January 2013 Phase 4
NCT01724723 National Taiwan University Hospital Hepatitis|Tuberculosis|hepatitisB December 2012 Phase 4
NCT01037062 Bristol-Myers Squibb Chronic Hepatitis B December 2003 Phase 2
NCT01243281 Chulalongkorn University Chronic Hepatitis B March 2011
NCT01627223 Taichung Veterans General Hospital|GlaxoSmithKline Chronic Hepatitis B July 2012 Phase 4
NCT01369199 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|University of Pittsburgh Hepatitis B May 2012 Phase 3
NCT03062813 Guangdong General Hospital Hepatitis B Virus Associated Nephrotic Syndrome February 1, 2017 Phase 4
NCT01765231 Peking University Hepatitis B January 2013 Phase 4
NCT00926757 Taipei Veterans General Hospital, Taiwan|Bristol-Myers Squibb Non Hodgkin's Lymphoma|Hepatitis B April 2009 Phase 4
NCT00975091 Bristol-Myers Squibb Chronic Hepatitis B Virus May 2004 Phase 3
NCT01914744 Fudan University Non-Hodgkin Lymphoma|Hepatitis B Reactivation February 2013 Phase 2
NCT01368497 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Hepatitis B September 2012 Phase 3
NCT01599130 Sun Yat-sen University Hepatitis B July 2012
NCT00704106 Pacific Health Foundation|Bristol-Myers Squibb Hepatitis B May 2008
NCT01354652 Asan Medical Center Lactic Acidosis May 2011 Phase 4
NCT01833611 National Cheng-Kung University Hospital Chronic Hepatitis September 2008 Phase 4
NCT01925820 National Taiwan University Hospital|Roche Pharma AG Chronic Hepatitis B January 2013 Phase 4
NCT00921180 National Taiwan University Hospital|National Science Council, Taiwan Hepatitis B, Chronic February 2007 Phase 4
NCT00625339 Yonsei University|Pusan National University Hospital Hepatitis B, Chronic February 2008 Phase 4
NCT00637663 Pusan National University Hospital|Yonsei University Hepatitis B, Chronic February 2008 Phase 4
NCT01639092 Asan Medical Center|Samsung Medical Center|Konkuk University Medical Center|Korea University Guro Hospital|Seoul National University Hospital Chronic Viral Hepatitis B Without Delta-agent September 2012 Phase 4
NCT01907230 Taipei Veterans General Hospital, Taiwan Rheumatoid Arthritis|Hepatitis B Reactivation|Exposure to Hepatitis B Virus July 2013 Phase 4
NCT00423891 Bristol-Myers Squibb Hepatitis B, Chronic June 30, 2007 Phase 1|Phase 2
NCT01711567 Korea University|Gilead Sciences Chronic Hepatitis B April 2013 Phase 4
NCT00718887 Bristol-Myers Squibb Hepatitis B, Chronic July 2008 Phase 4
NCT00625560 Yonsei University|Pusan National University Hospital Hepatitis B, Chronic February 2008 Phase 4
NCT01594905 Yonsei University|Bristol-Myers Squibb|Seoul St. Mary's Hospital|The Catholic University of Korea Chronic Hepatitis B August 2012 Phase 4
NCT01595685 Asan Medical Center Chronic Viral Hepatitis B Without Delta-agent May 2012 Phase 3
NCT00877760 Foundation for Liver Research Chronic Hepatitis B August 2009 Phase 4
NCT00395018 Bristol-Myers Squibb Hepatitis B, Chronic April 2007 Phase 3
NCT00597259 National Taiwan University Hospital|Bristol-Myers Squibb Chronic Hepatitis B January 2008 Phase 4
NCT01148576 Zhejiang University Chronic Hepatitis B|Hepatic Steatosis June 2010 Phase 4
NCT01079806 Bristol-Myers Squibb Chronic Hepatitis B Virus, Pediatric June 30, 2010 Phase 3
NCT02650271 Guangxi Medical University Hepatocellular Carcinoma July 2015 Phase 2|Phase 3
NCT02365402 Beijing Ditan Hospital Chronic Hepatitis B January 2013 Phase 4
NCT01254994 Sun Yat-sen University Liver Failure August 2007 Phase 2
NCT01323452 Foundation for Liver Research Entecavir for Chronic Hepatitis B Patients November 2010
NCT01023217 Asan Medical Center Hepatitis B, Chronic November 2009 Phase 4
NCT02241616 ShuGuang Hospital|Shanghai Zhongshan Hospital|Guangxi Ruikang Hospital|Hubei Hospital of Traditional Chinese Medicine|The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine|Huai'an No. 4 People's Hospital|Ruijin Hospital|Shenzhen Third People's Hospital|Beijing Ditan Hospital|Beijing YouAn Hospital|China-Japan Friendship Hospital|Tongji Hospital|Wenzhou Central Hospital|Jingmen No.1 People’s Hospital|Affiliated Hospital of Shandong Univercity of TCM|Guang'anmen Hospital of China Academy of Chinese Medical Sciences|The Ninth Hospital of Nanchang|The People's Hospital of Ningxia|Fifth Hospital of Shijiazhuang City|The Fifth People's Hospital of Suzhou|The Fifth People’s Hospital of Anyang Hepatitis B Virus Related Cirrhosis September 2014 Phase 4
NCT01326546 Chongqing Jiachen Biotechnology Ltd.|Third Military Medical University Chronic Hepatitis B June 2010 Phase 2
NCT00531167 Korea University|GlaxoSmithKline Chronic Hepatitis B April 2007 Phase 4
NCT01438424 Bristol-Myers Squibb Hepatitis B Virus|HBV January 2001 Phase 2
NCT00410072 Bristol-Myers Squibb Hepatitis B, Chronic April 2007 Phase 3
NCT00917761 National Taiwan University Hospital|National Science Council, Taiwan Hepatitis B, Chronic February 2007 Phase 4
NCT01906580 Beijing 302 Hospital Chronic Hepatitis B July 2011 Phase 4
NCT02368288 Beijing Ditan Hospital Chronic Hepatitis B January 2013 Phase 4
NCT00096811 Bristol-Myers Squibb Hepatitis B|Chronic Disease September 2003
NCT01639066 Asan Medical Center|Samsung Medical Center|Konkuk University Medical Center|Korea University Guro Hospital|Seoul National University Hospital Chronic Viral Hepatitis B Without Delta-agent September 2012 Phase 4
NCT01020565 Bristol-Myers Squibb Chronic Hepatitis B February 2003 Phase 2
NCT00412529 Novartis Pharmaceuticals|Novartis Hepatitis B|Chronic Hepatitis B December 2006 Phase 3
NCT01063036 Bristol-Myers Squibb Chronic Hepatitis B May 2010 Phase 3
NCT00371150 Bristol-Myers Squibb Hepatitis B Infection November 2006 Phase 4
NCT02241590 ShuGuang Hospital|Shanghai Zhongshan Hospital|Guangxi Ruikang Hospital|Hubei Hospital of Traditional Chinese Medicine|The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine|Huai'an No. 4 People's Hospital|Ruijin Hospital|Shenzhen Third People's Hospital|Beijing Ditan Hospital|Beijing YouAn Hospital|China-Japan Friendship Hospital|Tongji Hospital|Wenzhou Central Hospital|Jingmen No.1 People’s Hospital|Affiliated Hospital of Shandong Univercity of TCM|Guang'anmen Hospital of China Academy of Chinese Medical Sciences|The Ninth Hospital of Nanchang|The People's Hospital of Ningxia|Fifth Hospital of Shijiazhuang City|The Fifth People's Hospital of Suzhou|The Fifth People’s Hospital of Anyang Liver Cirrhosis Due to Hepatitis B Virus September 2014 Phase 4
NCT02532413 Wuhan Union Hospital, China Chronic Hepatitis B July 2015 Phase 4
NCT01588912 Pusan National University Yangsan Hospital Chronic Hepatitis B April 2012 Phase 4
NCT00388674 Bristol-Myers Squibb Chronic Hepatitis B December 18, 2006
NCT00393484 Bristol-Myers Squibb Chronic Hepatitis B February 2007 Phase 4
NCT01266005 Bukwang Pharmaceutical Chronic Hepatitis B August 2009 Phase 4
NCT01580202 Seoul National University Hospital Malignancy|Hepatitis B April 2012 Phase 3
NCT02849132 Beijing Friendship Hospital Hepatitis B|Liver Cirrhosis January 2016 Phase 4
NCT00940485 Hoffmann-La Roche Hepatitis B, Chronic April 2009 Phase 4
NCT00605384 Bristol-Myers Squibb Chronic Hepatitis B August 2008 Phase 3
NCT00662545 University of California, San Francisco|Bristol-Myers Squibb HIV Infections|Hepatitis B April 2008 Phase 4
NCT02075294 Ying-Jie Ji|Beijing 302 Hospital Hepatitis B, Chronic January 2010
NCT01022801 Bristol-Myers Squibb Chronic Hepatitis B August 2003 Phase 2
NCT00096785 Bristol-Myers Squibb Hepatitis B|Chronic Disease December 2004 Phase 3
NCT02589652 Huashan Hospital Chronic Hepatitis B October 2015
NCT02945956 ShuGuang Hospital|Ruijin Hospital|Shanghai Zhongshan Hospital|Longhua Hospital|Shanghai Public Health Clinical Center Portal Hypertension November 2016 Phase 4
NCT02482272 Asan Medical Center Hepatitis B, Chronic May 2015 Phase 4
NCT01037166 Bristol-Myers Squibb Chronic Hepatitis B December 2002 Phase 2
NCT00065507 Bristol-Myers Squibb Hepatitis B August 2003 Phase 3
NCT00986778 Bristol-Myers Squibb Hepatitis B, Chronic December 2009 Phase 4
NCT01270178 Taipei Veterans General Hospital, Taiwan Chronic Hepatitis B|Hepatocellular Carcinoma January 2011
NCT02263079 Hoffmann-La Roche Hepatitis B, Chronic June 16, 2014 Phase 3
NCT01242787 LG Life Sciences Chronic Hepatitis B August 2010 Phase 2
NCT03032536 Alios Biopharma Inc. Hepatitis B|Chronic Hepatitis B|Viral Hepatitis B January 31, 2017 Phase 1
NCT00051038 Bristol-Myers Squibb Hepatitis B September 2002 Phase 2|Phase 3
NCT01926288 Jiangsu Chia-tai Tianqing Pharmaceutical Co.,Ltd Chronic Hepatitis B October 2008 Phase 4
NCT01026610 LG Life Sciences Chronic Hepatitis B August 2009 Phase 2
NCT02417207 Third Affiliated Hospital, Sun Yat-Sen University Hepatitis B|Liver Transplantation April 2015 Phase 4
NCT02881008 Hepatera Ltd. Chronic Hepatitis B August 2012 Phase 1|Phase 2
NCT00410202 Bristol-Myers Squibb Hepatitis B, Chronic March 2008 Phase 3
NCT02945982 ShuGuang Hospital|Ruijin Hospital|Shanghai Zhongshan Hospital|Longhua Hospital|Shanghai Public Health Clinical Center Portal Hypertension December 2016 Phase 4
NCT01715987 New Discovery LLC Hepatitis B October 2012
NCT01220596 Hanyang University|Roche Pharma AG Hepatitis B, Chronic June 2010 Phase 3
NCT01938820 Beijing Friendship Hospital|Peking University People's Hospital|RenJi Hospital|Peking University|Shanghai Zhongshan Hospital|Fudan University|Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine|Shanghai Public Health Clinical Center|Nanfang Hospital of Southern Medical University|Sir Run Run Shaw Hospital|Beijing YouAn Hospital|Peking University First Hospital|Beijing 302 Hospital|Peking Union Medical College Hospital|Beijing Ditan Hospital|Beijing Tiantan Hospital|Huashan Hospital|Tongji Hospital|Tang-Du Hospital|Fifth Hospital of Shijiazhuang City|Logistics University of Chinese People's Armed Police Forces|The First Affiliated Hospital of Shanxi Medical University|The Affiliated Hospital of Yanbian University Liver Cirrhosis June 2013 Phase 4
NCT01943617 Beijing Friendship Hospital|Peking University People's Hospital|RenJi Hospital|Peking University|Shanghai Zhongshan Hospital|Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine|Shanghai Public Health Clinical Center|Nanfang Hospital of Southern Medical University|Sir Run Run Shaw Hospital|Beijing YouAn Hospital|Peking University First Hospital|Beijing 302 Hospital|Peking Union Medical College Hospital|Beijing Ditan Hospital|Beijing Tiantan Hospital|Huashan Hospital|Tongji Hospital|Tang-Du Hospital|Fifth Hospital of Shijiazhuang City|Logistics University of Chinese People's Armed Police Forces|The First Affiliated Hospital of Shanxi Medical University|The Affiliated Hospital of Yanbian University Liver Cirrhosis June 2013 Phase 4
NCT01918631 Chinese University of Hong Kong Chronic Heptitis B August 2013
NCT01694264 Seoul National University Hospital|Konkuk University Medical Center|Kyungpook National University|Kyunghee University Medical Center|Kyung Hee University Hospital at Gangdong|Gachon University Gil Medical Center|Daegu Catholic University Medical Center|Eulji University Hospital|SMG-SNU Boramae Medical Center|The Catholic University of Korea|Severance Hospital|Ajou University School of Medicine|Ewha Womans University Mokdong Hospital|Inha University Hospital|Chonnam National University Hospital|Chonbuk National University Hospital|Chungnam National University Hospital|Hallym University Medical Center|Hanyang University|Dong-A University|Korea University Guro Hospital Chronic Hepatitis B|Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis|Juvenile Idiopathic Arthritis September 1, 2012 Phase 3
NCT01938781 Beijing Friendship Hospital|Peking University People's Hospital|RenJi Hospital|Peking University|Shanghai Zhongshan Hospital|Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine|Shanghai Public Health Clinical Center|Nanfang Hospital of Southern Medical University|Sir Run Run Shaw Hospital|Beijing YouAn Hospital|Peking University First Hospital|Beijing 302 Hospital|Peking Union Medical College Hospital|Beijing Ditan Hospital|Beijing Tiantan Hospital|Huashan Hospital|Tongji Hospital|Tang-Du Hospital|Fifth Hospital of Shijiazhuang City|Logistics University of Chinese People's Armed Police Forces|The First Affiliated Hospital of Shanxi Medical University|The Affiliated Hospital of Yanbian University Liver Fibrosis June 2013 Phase 4
NCT00298363 Gilead Sciences Chronic Hepatitis B April 2006 Phase 2
NCT00994773 Bader, Ted, M.D. Hepatitis B December 2009 Phase 1
NCT01341743 Nanfang Hospital of Southern Medical University|JiangSu Chia-Tai Tianqin Pharmacy Co.Ltd Hepatitis B December 2010 Phase 4
NCT01829685 Nanfang Hospital of Southern Medical University|Major Science and Technology Special Project of China Eleventh Five-year Chronic Hepatitis B|Inadequate Response|Nucleos(t)Ide Analogues Treatment March 2013 Phase 4
NCT01892241 Third Affiliated Hospital, Sun Yat-Sen University Antiviral Treatment of Chronic Hepatitis B January 2010 Phase 3
NCT01341106 RWTH Aachen University|Hannover Medical School|Hannover Clinical Trial Center GmbH Hepatitis B, Chronic|Liver Fibrosis April 2011 Phase 4
NCT00614471 Hoffmann-La Roche Hepatitis B, Chronic August 2007 Phase 4
NCT01139203 Shanghai Jiao Tong University School of Medicine|Zhejiang University Liver Transplantation|Hepatitis B August 2009
NCT00036608 Bristol-Myers Squibb Chronic Hepatitis B January 2002 Phase 3
NCT00035633 Bristol-Myers Squibb Chronic Hepatitis B December 2001 Phase 3
NCT00035789 Bristol-Myers Squibb Chronic Hepatitis B November 2001 Phase 3
NCT01179594 Hoffmann-La Roche Hepatitis B, Chronic September 18, 2010 Phase 4
NCT02726789 Replicor Inc. Hepatitis B, Chronic October 2012 Phase 2
NCT00922207 Hoffmann-La Roche Hepatitis B, Chronic May 7, 2010 Phase 4
NCT01217632 FibroGen Liver Fibrosis Due to Chronic Hepatitis B Infection August 2010 Phase 2
NCT00931229 National Health Research Institutes, Taiwan|National Taiwan University Hospital|Mackay Memorial Hospital|China Medical University Hospital|Chi Mei Medical Hospital|Taichung Veterans General Hospital|Kaohsiung Veterans General Hospital.|Kaohsiung Medical University Non-Hodgkin's Lymphoma June 2009
NCT02452528 Arrowhead Pharmaceuticals Chronic Hepatitis B August 2015 Phase 2
NCT02097004 Seoul National University Hospital Hepatitis B, Chronic April 2014 Phase 4
NCT00823550 Yonsei University|Severance Hospital|Kangbuk Samsung Hospital|Konkuk University Hospital|Chung-Ang University|Ajou University|Inha University Hospital|Soonchunhyang University Hospital|The Catholic University of Korea|Hallym University Medical Center|Kyungpook National University|Keimyung University|Korea University Anam Hospital|Korea University|Hanyang University|Inje University|Pusan National University Hospital|Bristol-Myers Squibb Hepatitis B, Chronic January 2009 Phase 4
NCT02829359 Guangxi Medical University Liver Cancer July 2012 Phase 2|Phase 3
NCT02327416 Tongji Hospital|Xiamen Amoytop Biotech Co., Ltd. Hepatitis B, Chronic October 2014 Phase 3
NCT01834508 Nanfang Hospital of Southern Medical University|Major Science and Technology Special Project of China 12th Five-year Chronic Hepatitis B March 2013 Phase 4
NCT01894269 Sun Yat-sen University Hepatocellular Carcinoma July 2013 Phase 4
NCT00768157 Sun Yat-sen University Hepatocellular Carcinoma|Hepatitis B Virus|Recurrence April 2007 Phase 4
NCT02360592 Tongji Hospital|Beijing Kawin Technology Share-Holding Co., Ltd.|Fujian Cosunter Pharmaceutical Co. Ltd Hepatitis B, Chronic April 2014 Phase 4
NCT01813487 Genexine, Inc. Chronic Hepatitis B February 2013
NCT01023230 Dynavax Technologies Corporation Hepatitis B, Chronic September 2009 Phase 1
NCT02973646 Third Affiliated Hospital, Sun Yat-Sen University Chronic Hepatitis b January 2016 Phase 4
NCT01456312 Gangnam Severance Hospital|Roche Pharma AG Hepatitis B, Chronic September 2012 Phase 4
NCT02499562 Shanghai Genomics, Inc. Hepatitis B, Chronic July 2015 Phase 2
NCT03164889 Beijing 302 Hospital Hepatitis B, Chronic January 2017
NCT02883647 Third Affiliated Hospital, Sun Yat-Sen University Chronic Hepatitis b January 2014
NCT02505009 Chang Gung Memorial Hospital Chronic Hepatitis B May 2015 Phase 4
NCT01204762 Bristol-Myers Squibb Hepatitis B Virus November 2010 Phase 2
NCT01720238 Beijing Friendship Hospital|Peking University First Hospital|Peking University People's Hospital|Beijing YouAn Hospital|Beijing Tiantan Hospital|Beijing Ditan Hospital|Peking Union Medical College Hospital|Beijing 302 Hospital Liver Cirrhosis|Hepatitis B March 2012
NCT02288208 TetraLogic Pharmaceuticals Hepatitis B November 2014 Phase 1
NCT02577029 Arrowhead Pharmaceuticals Hepatitis B|Hepatitis D December 2015 Phase 2
NCT00824707 Eastern Hepatobiliary Surgery Hospital Primary Liver Cancer December 2008
NCT03018821 Xi'an Traditional Medicine Hospital Hepatitis B, Chronic January 2017
NCT01018381 The 108 Military Central Hospital|Charles Drew University of Medicine and Science Hepatocellular Carcinoma|Hepatitis B June 2006
NCT00555334 Sun Yat-sen University Hepatocellular Carcinoma|Liver Cancer November 2007 Phase 4
NCT02908191 Assembly Biosciences Chronic Hepatitis B November 2016 Phase 1
NCT01027065 Cytheris SA Chronic Hepatitis B December 2009 Phase 1|Phase 2
NCT02391805 Hoffmann-La Roche Hepatitis B, Chronic May 17, 2015 Phase 2
NCT03084250 Shanghai Nanhui Nanhua Hospital Hepatitis B March 10, 2017 Phase 4
NCT01083251 Ziv Hospital Hepatitis B Virus March 2010
NCT02615639 Third Affiliated Hospital, Sun Yat-Sen University|Shanghai Jiao Tong University School of Medicine Chronic Hepatitis B November 2015 Phase 1|Phase 2
NCT02555943 Humanity & Healthy GI and Liver Centre|Beijing 302 Hospital|Nanfang Hospital of Southern Medical University Chronic Hepatitis C Infection|HBV Coinfection|Hepatitis B Reactivation February 2015 Phase 2|Phase 3
NCT02281266 Jia Fan|SciClone Pharmaceuticals|Fudan University Curable Hepatitis B Virus-Related Hepatocellular Carcinoma January 2015 Phase 4
NCT03109730 Assembly Biosciences Chronic Hepatitis b July 2017 Phase 1|Phase 2
NCT02560649 Ruijin Hospital Chronic Hepatitis B May 2015 Phase 4
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References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.3865 mL 16.9325 mL 33.8650 mL
5 mM 0.6773 mL 3.3865 mL 6.7730 mL
10 mM 0.3387 mL 1.6933 mL 3.3865 mL
Cell Assay
[1]

BMS 200475 is prepared in phosphate-buffered saline (PBS) and diluted with appropriate medium containing 2% fetal bovine serum. HepG2 2.2.15 cells are plated at a density of 5×105 cells per well on 12-well Biocoat collagen-coated plates and are maintained in a confluent state for 2 to 3 days before being overlaid with 1 mL of medium spiked with BMS 200475. Quantification of HBV was performed on day 10[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
M.Wt

295.29

Formula

C₁₂H₁₇N₅O₄

CAS No.

209216-23-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 32 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 99.66%

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Product Name:
Entecavir monohydrate
Cat. No.:
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