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Entecavir

HY-13623

(BMS200475; SQ34676)

Entecavir

Entecavir Chemical Structure

Entecavir(BMS200475; SQ34676) is a guanosine analogue that inhibits reverse transcription, DNA replication and transcription in the viral replication process; oral antiHBV drug.

Size Price Stock Quantity
10 mM * 1 mL in DMSO $139 In-stock
10 mg $126 In-stock
50 mg $189 In-stock
100 mg $338 In-stock
200 mg Get quote
500 mg Get quote
Size Price Stock Quantity
10 mM * 1 mL in DMSO €136 In-stock
10 mg €123 In-stock
50 mg €185 In-stock
100 mg €331 In-stock
200 mg Get quote
500 mg Get quote

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Inquiry Information
Product name: Entecavir
Cat. No.: HY-13623

Entecavir Data Sheet

  • Network Version

    DataSheet

Related Compound Libraries

Biological Activity of Entecavir

Entecavir(BMS200475; SQ34676) is a guanosine analogue that inhibits reverse transcription, DNA replication and transcription in the viral replication process; oral antiHBV drug.
IC50 value:
Target: AntiHBV drug
Both entecavir and adefovir dipivoxil maintain activity against hepatitis B virus in patients with chronic hepatitis B who are refractory to lamivudine, and both agents are reasonable first-line treatment options. Longer trials involving nucleoside-naive, lamivudine-refractory patients are needed to determine entecavir's optimal treatment duration, long-term safety, and durability of response, including rate of resistance [1]. Entecavir is used to treat chronic hepatitis B. It also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection. However, entecavir is not active against HIV.

 

Chemical Information

M.Wt 277.28 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Formula C₁₂H₁₅N₅O₃
CAS No 142217-69-4
Solvent & Solubility

DMSO: ≥ 44 mg/mL

Preparing Stock Solutions

1 mg 5 mg 10 mg
1 mM 3.6065 mL 18.0323 mL 36.0646 mL
5 mM 0.7213 mL 3.6065 mL 7.2129 mL
10 mM 0.3606 mL 1.8032 mL 3.6065 mL

References on Entecavir

Other Forms

Inhibitor Kit

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