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Entecavir Chemical Structure
|Product name: Entecavir|
|Cat. No.: HY-13623|
Entecavir(BMS200475; SQ34676) is a guanosine analogue that inhibits reverse transcription, DNA replication and transcription in the viral replication process; oral antiHBV drug.
Target: AntiHBV drug
Both entecavir and adefovir dipivoxil maintain activity against hepatitis B virus in patients with chronic hepatitis B who are refractory to lamivudine, and both agents are reasonable first-line treatment options. Longer trials involving nucleoside-naive, lamivudine-refractory patients are needed to determine entecavir's optimal treatment duration, long-term safety, and durability of response, including rate of resistance . Entecavir is used to treat chronic hepatitis B. It also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection. However, entecavir is not active against HIV.
|M.Wt||277.28||Storage||Please store the product under the recommended conditions in the Certificate of Analysis.|
|Solvent & Solubility||
DMSO: ≥ 44 mg/mL
|1 mg||5 mg||10 mg|
|1 mM||3.6065 mL||18.0323 mL||36.0646 mL|
|5 mM||0.7213 mL||3.6065 mL||7.2129 mL|
|10 mM||0.3606 mL||1.8032 mL||3.6065 mL|
CAS No.: 209216-23-9 In-stock
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