521-48-2
Chemical Structure
Isoxanthohumol
- CAS No.: 521-48-2
- Formula:C21H22O5
- Molecular Weight:354.40
IUPAC Name: 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one
InChIKey: YKGCBLWILMDSAV-UHFFFAOYSA-N
SMILES: OC1=CC(OC)=C2C(CC(OC2=C1C/C=C(C)\C)C3=CC=C(C=C3)O)=O
Biological Activity: Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases[1][2][3][4][5].
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Isoxanthohumol | 99.91% | Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases. | ||||||||||||||||||||
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Isoxanthohumol (Standard) | ≥98% | Isoxanthohumol (Standard) is the analytical standard of Isoxanthohumol (HY-N2584A). This product is intended for research and analytical applications. Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases. | ||||||||||||||||||||
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- [1]. Yang JY, et al. Effect of xanthohumol and isoxanthohumol on 3T3-L1 cell apoptosis and adipogenesis. Apoptosis. 2007 Nov;12(11):1953-63. [Content Brief]
- [2]. Yan YF, et al. The Antifungal Mechanism of Isoxanthohumol from Humulus lupulus Linn. Int J Mol Sci. 2021 Oct 7;22(19):10853. [Content Brief]
- [3]. Krajnović T, et al. The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model. Food Chem Toxicol. 2019 Jul;129:257-268. [Content Brief]
- [4]. Yang YN, et al. Therapeutic effects and mechanisms of isoxanthohumol on DSS-induced colitis: regulating T cell development, restoring gut microbiota, and improving metabolic disorders. Inflammopharmacology. 2024 Jun;32(3):1983-1998. [Content Brief]
- [5]. Żołnierczyk AK, et al. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82. [Content Brief]
