347337-33-1
347337-33-1
Chemical Structure
MLS8969
- CAS 番号: 347337-33-1
- Formula:C19H15ClN2O4
- Molecular Weight:370.79
IUPAC Name: N-(4-(5-chloro-2-methoxybenzamido)phenyl)furan-2-carboxamide
InChIKey: SAJGBRXZFCMPCS-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=C1)NC(=O)C2=CC(Cl)=CC=C2OC)C=3OC=CC3
Biological Activity: MLS8969 is a selective human cytomegalovirus (HCMV) entry inhibitor with an EC50 of 0.12 μM (HFFs). MLS8969 reduces viral protein levels and inhibits nuclear staining of HCMV pp65. MLS8969 can be used in studies related to human cytomegalovirus infection[1][2].
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MLS8969 | MLS8969 is a selective human cytomegalovirus (HCMV) entry inhibitor with an EC50 of 0.12 μM (HFFs). MLS8969 reduces viral protein levels and inhibits nuclear staining of HCMV pp65. MLS8969 can be used in studies related to human cytomegalovirus infection. | |||||||||||||||||||||
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References
- [1]. Kapoor A, et al. Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus. J Med Chem. 2020;63(8):3896-3907. [Content Brief]
- [2]. Guo X, et al. The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides. Viruses. 2022;14(2):234. Published 2022 Jan 25. [Content Brief]
Keywords
