1. Anti-infection
  2. CMV
  3. Brincidofovir

Brincidofovir (Synonyms: CMX001; HDP-CDV)

Cat. No.: HY-14532 Purity: >98.0%
Handling Instructions

Brincidofovir (CMX001; HDP-CDV) is an orally active, lipophilic form of cidofovir (CDV); has enhanced activity in vitro and in vivo compared to CDV against certain herpesviruses, adenoviruses and orthopoxviruses.

For research use only. We do not sell to patients.

Brincidofovir Chemical Structure

Brincidofovir Chemical Structure

CAS No. : 444805-28-1

Size Stock
10 mM * 1 mL in DMSO Get quote
2 mg USD 480 Get quote
5 mg USD 720 Get quote
10 mg USD 1140 Get quote
25 mg USD 2160 Get quote
50 mg USD 4320 Get quote

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  • Biological Activity

  • Technical Information

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Description

Brincidofovir (CMX001; HDP-CDV) is an orally active, lipophilic form of cidofovir (CDV); has enhanced activity in vitro and in vivo compared to CDV against certain herpesviruses, adenoviruses and orthopoxviruses.

IC50 & Target

EC50: 5.5 nM (anti-CMV, in PDA at 7 dpi)

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 1 mg/mL (1.78 mM; adjust pH to 8 with NaOH and heat to 50°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7803 mL 8.9017 mL 17.8034 mL
5 mM 0.3561 mL 1.7803 mL 3.5607 mL
10 mM 0.1780 mL 0.8902 mL 1.7803 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

561.69

Formula

C₂₇H₅₂N₃O₇P

CAS No.

444805-28-1

SMILES

NC1=NC(N(C[[email protected]@H](CO)OCP(O)(OCCCOCCCCCCCCCCCCCCCC)=O)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Brincidofovir
Cat. No.:
HY-14532
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Brincidofovir

Cat. No.: HY-14532