1. Anti-infection
  2. Influenza Virus
  3. Nucleozin

Nucleozin 

Cat. No.: HY-50001 Purity: 99.45%
Handling Instructions

Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.

For research use only. We do not sell to patients.

Nucleozin Chemical Structure

Nucleozin Chemical Structure

CAS No. : 341001-38-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 74 In-stock
Estimated Time of Arrival: December 31
5 mg USD 67 In-stock
Estimated Time of Arrival: December 31
10 mg USD 108 In-stock
Estimated Time of Arrival: December 31
25 mg USD 216 In-stock
Estimated Time of Arrival: December 31
50 mg USD 384 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 3 publication(s) in Google Scholar

Top Publications Citing Use of Products

    Nucleozin purchased from MCE. Usage Cited in: Antiviral Res. 2017 Jul;143:106-112.

    MDCK cells are infected with H1N1/09pdm at an MOI of 10 in the presence of DMSO, CAE (60 μM) or Nucleozin (1 μM). At 3 h later, cells are fixed by 4% paraformaldehyde and NP is detected by IFA. Nuclei are stained with DAPI. Immunofluorescence is observed with a Nikon A1 confocal microscope.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References

    Description

    Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. IC50 Value: Target: Influenza Virus NP Nucleozin targets influenza A nucleoprotein, a multifunctional, RNA-binding protein necessary for virus replication. It induces the formation of nucleoptotein aggregates and inhibits its accumulation, interfering with viral replication. EC50 is in the nM range. Nucleozin is effective in H1N1, H3N2, and H5N1 flu virus strains.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 28.66 mg/mL (67.14 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.3427 mL 11.7137 mL 23.4274 mL
    5 mM 0.4685 mL 2.3427 mL 4.6855 mL
    10 mM 0.2343 mL 1.1714 mL 2.3427 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
    Molecular Weight

    426.85

    Formula

    C₂₁H₁₉ClN₄O₄

    CAS No.

    341001-38-5

    SMILES

    CC1=C(C(C2=CC=CC=C2)=NO1)C(N3CCN(C4=C(C=C(C=C4)[N+]([O-])=O)Cl)CC3)=O

    Shipping

    Room temperature in continental US; may vary elsewhere

    Purity: 99.45%

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

    Inquiry Online

    Your information is safe with us. * Required Fields.

    Product name

     

    Salutation

    Applicant name *

     

    Email address *

    Phone number *

     

    Organization name *

    Country or Region *

     

    Requested quantity *

    Remarks

    Bulk Inquiry

    Inquiry Information

    Product Name:
    Nucleozin
    Cat. No.:
    HY-50001
    Quantity:

    Nucleozin

    Cat. No.: HY-50001