Cidofovir-¹³C,¹⁵N₂ disodium  (Synonyms: GS 0504-¹³C,¹⁵N₂ disodium; HPMPC-¹³C,¹⁵N₂ disodium; (S)-HPMPC-¹³C,¹⁵N₂ disodium)

Cidofovir-¹³C,¹⁵N₂ disodium (GS 0504-¹³C,¹⁵N₂ disodium) is the ¹³C- and ¹⁵N-labeled Cidofovir disodium (HY-167911). Cidofovir sodium is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir sodium inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir sodium induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer^[1][3]. Cidofovir sodium also has anti-orthopoxvirus and anti-variola activities^[4].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

326.13

C₇¹³CH₁₂N¹⁵N₂Na₂O₆P

127749-27-3

OC[C@@H](OCP(O[Na])(O[Na])=O)C[15N]1C=CC(N)=[15N][13C]1=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.