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Cat. No.: HY-167911S

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Cidofovir-¹³C,¹⁵N₂ disodium

Name: Cidofovir-13C,15N2 disodium
Brand: MedChemExpress
SKU: HY-167911S
Availability: PreOrder

(Synonyms: GS 0504-¹³C,¹⁵N₂ disodium; HPMPC-¹³C,¹⁵N₂ disodium; (S)-HPMPC-¹³C,¹⁵N₂ disodium)

Cidofovir-¹³C,¹⁵N₂ disodium (GS 0504-¹³C,¹⁵N₂ disodium) is the ¹³C- and ¹⁵N-labeled Cidofovir disodium (HY-167911). Cidofovir sodium is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir sodium inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir sodium induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer. Cidofovir sodium also has anti-orthopoxvirus and anti-variola activities.

For research use only. We do not sell to patients.

Formula: C₇¹³CH₁₂N¹⁵N₂Na₂O₆P
Molecular Weight:326.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cidofovir-¹³C,¹⁵N₂ disodium Chemical Structure

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Biological Activity
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- Application
Chemical Information
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Biological Activity

Description

Cidofovir-¹³C,¹⁵N₂ disodium (GS 0504-¹³C,¹⁵N₂ disodium) is the ¹³C- and ¹⁵N-labeled Cidofovir disodium (HY-167911). Cidofovir sodium is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir sodium inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir sodium induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer^[1]^[3]. Cidofovir sodium also has anti-orthopoxvirus and anti-variola activities^[4].

All Endogenous Metabolite Isoforms :

All DNA/RNA Synthesis Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 127749-27-3
Molecular Weight 326.13
Formula C₇¹³CH₁₂N¹⁵N₂Na₂O₆P
SMILES

OC[C@@H](OCP(O[Na])(O[Na])=O)C[15N]1C=CC(N)=[15N][13C]1=O
Synonyms

GS 0504-¹³C,¹⁵N₂ disodium; HPMPC-¹³C,¹⁵N₂ disodium; (S)-HPMPC-¹³C,¹⁵N₂ disodium
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.