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Cidofovir sodium

(Synonyms: GS 0504 sodium; HPMPC sodium; (S)-HPMPC sodium)
14 Cited Publications
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Based on 14 publication(s) in Google Scholar

Cidofovir sodium is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir sodium inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir sodium induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer. Cidofovir sodium also has anti-orthopoxvirus and anti-variola activities.

For research use only. We do not sell to patients.

  • CAS No.: 127749-27-3
  • Formula: C8H12N3Na2O6P
  • Molecular Weight:323.15
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Cidofovir sodium Chemical Structure
    Cidofovir sodium Chemical Structure
  • Experimental Validation Results for Cidofovir sodium
  • Experimental Validation Results for Cidofovir sodium
  • Experimental Validation Results for Cidofovir sodium
  • Experimental Validation Results for Cidofovir sodium
  • Experimental Validation Results for Cidofovir sodium
CAS No.: 127749-27-3
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  • Cidofovir sodium Chemical Structure
    Cidofovir sodium Chemical Structure
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    Cidofovir sodium purchased from MedChemExpress. Usage Cited in: Pharmaceuticals (Basel). 2025 Oct 16;18(10):1560. [Abstract]

    Customer Validation
     The cytotoxicity of three reference compounds (GCV, CDV (Cidofovir), and BCV) on COS-7 cells was tested.

  • 1/16

    Cidofovir sodium purchased from MedChemExpress. Usage Cited in: Virol Sin. 2025 Mar 25:S1995-820X(25)00031-8. [Abstract]

    Customer Validation
     HEK293T cells were transfected with pHBoV1-HiBiTNS1 in the presence of Cidofovir (200 ​μM), favipiravir (50 ​μM), ivermectin (10 ​μM), nevirapine (50 ​μM), remdesivir (10 ​μM), ribavirin (50 ​μM), sofosbuvir (50 ​μM), or zidovudin (50 ​μM). At 72 ​h post-transfection, the Nano-Glo luciferase assay was performed.

  • 1/16

    Cidofovir sodium purchased from MedChemExpress. Usage Cited in: J Virol. 2025 Jan 23:e0153924. [Abstract]

    Customer Validation
     Antiviral activity of cidofovir against HBoV1. MA104 cells were treated with 50, 100, 200, 400 µM cidofovir for 6 h and then infected with HBoV1 for 12 h, and the intracellular viral DNA copies were detected at 96 h.p.i.

  • 1/16

    Cidofovir sodium purchased from MedChemExpress. Usage Cited in: Poult Sci. 2024 Dec;103(12):104238. [Abstract]

    Customer Validation
     DEFs infected DPV at MOI=1, then treated with Cidofovir (10 nmol) for 1 h, 2 h, 3 h, 4 h, 6 h, 8 h, 10 h, 12 h, 14 h and 16 h, qRT-PCR detected DPV copy numbers in the supernatant.

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    Cidofovir sodium purchased from MedChemExpress. Usage Cited in: Emerg Microbes Infect. 2023 Dec;12(1):2208682. [Abstract]

    Customer Validation
     Cytotoxicity of Cidofovir and its Inhibition efficiency on WIBP-MPXV-001

  • Cidofovir sodium