1. Anti-infection
  2. CMV
  3. Cidofovir dihydrate

Cidofovir dihydrate (Synonyms: HPMPC dihydrate; (S)-HPMPC dihydrate)

Cat. No.: HY-17438A
Handling Instructions

Cidofovir dehydrate is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis, which suppresses virus replication by selective inhibition of viral DNA synthesis.

For research use only. We do not sell to patients.

Cidofovir dihydrate Chemical Structure

Cidofovir dihydrate Chemical Structure

CAS No. : 149394-66-1

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100 mg USD 156 Get quote

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Description

Cidofovir dehydrate is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis, which suppresses virus replication by selective inhibition of viral DNA synthesis. Target: CMV DNA polymerase Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. It is an acyclic nucleoside phosphonate, and is therefore independent of phosphorylation by viral enzymes, unlike acyclovir. Cidofovir was discovered at the Institute of Organic Chemistry and Biochemistry, Prague, by Antonín Hol?, and developed by Gilead Sciences and is marketed with the brand name Vistide by Gilead in the USA, and by Pfizer elsewhere. Maintenance therapy with cidofovir involves an infusion only once every two weeks, making it a convenient treatment option. Because dosing is relatively infrequent, a permanent catheter is not necessary for infusions.

Clinical Trial
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

315.22

Formula

C₈H₁₈N₃O₈P

CAS No.

149394-66-1

SMILES

OC[[email protected]@H](OCP(O)(O)=O)CN1C=CC(N)=NC1=O.O.O

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Cidofovir dihydrate
Cat. No.:
HY-17438A
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Cidofovir dihydrate

Cat. No.: HY-17438A