Gly-Gly-Gly-PEG3-TCO

Name: Gly-Gly-Gly-PEG3-TCO
Brand: MedChemExpress
SKU: HY-141190
Rating: 4.5 (0 reviews)

Cat. No.: HY-141190 Pureza: 99.90%: Ficha de datos
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Gly-Gly-Gly-PEG3-TCO is a 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Gly-Gly-Gly-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

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Gly-Gly-Gly-PEG3-TCO Estructura química

No. CAS : 2353409-81-9

Tamaño	Stock	Cantidad
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
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50 mg	Obtener un presupuesto

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Other Forms of Gly-Gly-Gly-PEG3-TCO:

Gly-Gly-Gly-PEG3-TCO TFA Obtener un presupuesto

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•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas ADC Linker:

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Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

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Descripciòn

Gly-Gly-Gly-PEG3-TCO is a 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1]. Gly-Gly-Gly-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

515.60

Fòrmula

C₂₃H₄₁N₅O₈

No. CAS

2353409-81-9

Appearance

Oil

Color

Off-white to light yellow

SMILES

NCC(NCC(NCC(NCCOCCOCCOCCNC(OC1CC/C=C\CCC1)=O)=O)=O)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Purity: 99.90%

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Ficha de datos (262 KB) SDS (393 KB)

COA (241 KB) HNMR (284 KB) RP-HPLC (237 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. [Content Brief]