1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. TCO-PEG4-VC-PAB-MMAE

TCO-PEG4-VC-PAB-MMAE 

Cat. No.: HY-148057 Purity: 98.04%
Handling Instructions

TCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162).

For research use only. We do not sell to patients.

TCO-PEG4-VC-PAB-MMAE Chemical Structure

TCO-PEG4-VC-PAB-MMAE Chemical Structure

CAS No. : 2758671-45-1

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Description

TCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162)[1].

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1522.91

Formula

C78H127N11O19

CAS No.
SMILES

CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C)[[email protected]@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C(OCC3=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCOCCOCCOCCOCCNC(OC4CC/C=C/CCC4)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
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Product Name:
TCO-PEG4-VC-PAB-MMAE
Cat. No.:
HY-148057
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