27740-01-8
Chemical Structure
Scutellarin
- No. CAS: 27740-01-8
- Formula:C21H18O12
- Molecular Weight:462.36
IUPAC Name: (2S,3S,4S,5R,6S)-6-((5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChIKey: DJSISFGPUUYILV-ZFORQUDYSA-N
SMILES: O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3C(O)=O)=C4O)C2=C4O
Biological Activity: Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively.
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Scutellarin | 99.57% | Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively. | ||||||||||||||||||||
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Scutellarin (Standard) | 98.03% | Scutellarin (Standard) is the analytical standard of Scutellarin. This product is intended for research and analytical applications. Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively. | ||||||||||||||||||||
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Similarity Score 0.91
HY-N6925Scutellarin methyl ester -
Similarity Score 0.91
HY-N17775Scutellarein 4'-methyl ether 7-O-glucuronide -
Similarity Score 0.90
HY-167859Hispidulin 7-glucuronide -
Similarity Score 0.88
HY-N0197Baicalin -
Similarity Score 0.86
HY-N9925Plantaginin -
Similarity Score 0.83
HY-N1454Apigenin-7-glucuronide -
Similarity Score 0.83
HY-N18372Hispidulin 7-O-glucuronide methyl ester -
Similarity Score 0.83
HY-N7643Comanthoside B -
Similarity Score 0.81
HY-N4297Baicalin methyl ester -
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