507475-17-4
507475-17-4
Chemical Structure
TPCA-1
- CAS No.: 507475-17-4
- Formula:C12H10FN3O2S
- Molecular Weight:279.29
IUPAC Name: 5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide
InChIKey: SAYGKHKXGCPTLX-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC(N)=O)SC(C2=CC=C(F)C=C2)=C1)N
Biological Activity: TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM. TPCA-1 is an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation.
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TPCA-1 | 98.75% | TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM. TPCA-1 is an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation. | ||||||||||||||||||||
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TPCA-1 (Standard) | ≥98% | TPCA-1 (Standard) is the analytical standard of TPCA-1 (HY-10074). This product is intended for research and analytical applications. TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM. TPCA-1 is an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation. | ||||||||||||||||||||
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Keywords
