1. Cell Cycle/DNA Damage
    Epigenetics
  2. HDAC
  3. HDAC4 Inhibitors

HDAC4 Inhibitors

HDAC

HDAC1

HDAC2

HDAC3

HDAC4

HDAC5

HDAC6

HDAC7

HDAC8

HDAC9

HDAC10

HDAC11

HD1

HD2

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Sorry. There is currently no product that acts on isoform HDAC4 together.

Please try each isoform separately.

HDAC4 Specific Inhibitors
Product Name HDAC4 HDAC HDAC1 HDAC2 HDAC3 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2 HDAC4 Selectivity Purity
Romidepsin
HDAC4, IC50: 510 nM
 
HDAC1, IC50: 36 nM
HDAC2, IC50: 47 nM
   
HDAC6, IC50: 14000 nM
              Pan Inhibitor 99.98%
Ricolinostat
HDAC4, IC50: 7000 nM
 
HDAC1, IC50: 58 nM
HDAC2, IC50: 48 nM
HDAC3, IC50: 51 nM
HDAC5, IC50: 5000 nM
HDAC6, IC50: 4.7 nM
HDAC7, IC50: 1400 nM
HDAC8, IC50: 100 nM
          Pan Inhibitor 99.35%
Tubacin
HDAC4, IC50: 17.30 μM
 
HDAC1, IC50: 1.40 μM
HDAC2, IC50: 6.27 μM
HDAC3, IC50: 1.27 μM
HDAC5, IC50: 3.35 μM
HDAC6, IC50: 4 nM
HDAC7, IC50: 9.70 μM
HDAC8, IC50: 1.27 μM
HDAC9, IC50: 4.31 μM
HDAC10, IC50: 3.71 μM
HDAC11, IC50: 3.79 μM
    Pan Inhibitor 98.87%
Fimepinostat
HDAC4, IC50: 409 nM
 
HDAC1, IC50: 1.7 nM
HDAC2, IC50: 5 nM
HDAC3, IC50: 1.8 nM
HDAC5, IC50: 674 nM
HDAC6, IC50: 27 nM
HDAC7, IC50: 426 nM
HDAC8, IC50: 191 nM
HDAC9, IC50: 554 nM
HDAC10, IC50: 2.8 nM
HDAC11, IC50: 5.4 nM
    Pan Inhibitor 99.95%
TMP195
HDAC4, IC50: 111 nM
       
HDAC5, IC50: 106 nM
HDAC6, IC50: 47800 nM
HDAC7, IC50: 46 nM
HDAC8, IC50: 11700 nM
HDAC9, IC50: 9 nM
        Pan Inhibitor 99.42%
Nexturastat A
HDAC4, IC50: 9.39 μM
 
HDAC1, IC50: 3.02 μM
HDAC2, IC50: 6.92 μM
HDAC3, IC50: 6.68 μM
HDAC5, IC50: 11.7 μM
HDAC6, IC50: 5.02 nM
HDAC7, IC50: 4.46 μM
HDAC8, IC50: 0.954 μM
HDAC9, IC50: 6.72 μM
HDAC10, IC50: 7.57 μM
HDAC11, IC50: 5.14 μM
    Pan Inhibitor 97.92%
Pracinostat
HDAC4, IC50: 56 nM
 
HDAC1, IC50: 49 nM
HDAC2, IC50: 96 nM
HDAC3, IC50: 43 nM
HDAC5, IC50: 47 nM
HDAC6, IC50: 1008 nM
HDAC7, IC50: 137 nM
HDAC8, IC50: 140 nM
HDAC9, IC50: 70 nM
HDAC10, IC50: 40 nM
HDAC11, IC50: 93 nM
    Pan Inhibitor 99.07%
Givinostat hydrochloride monohydrate
hHDAC4, IC50: 1059 nM
 
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC3, IC50: 157 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
Pan Inhibitor >98.0%
CUDC-101
HDAC4, IC50: 13.2 nM
HDAC, IC50: 4.4 nM
HDAC1, IC50: 4.5 nM
HDAC2, IC50: 12.6 nM
HDAC3, IC50: 9.1 nM
HDAC5, IC50: 11.4 nM
HDAC6, IC50: 5.1 nM
HDAC7, IC50: 373 nM
HDAC8, IC50: 79.8 nM
HDAC9, IC50: 67.2 nM
HDAC10, IC50: 26.1 nM
      Pan Inhibitor 99.59%
BML-210
HDAC4:MEF2
                          Pan Inhibitor 96.00%
Givinostat
hHDAC4, IC50: 1059 nM
 
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC3, IC50: 157 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
Pan Inhibitor
Givinostat hydrochloride
hHDAC4, IC50: 1059 nM
 
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC3, IC50: 157 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
Pan Inhibitor